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Methantheline Side Effects

The most commonly reported side effects of methantheline include dyspnoea, fatigue, and death, based on 43 FDA adverse event reports from 2005 to 2025.

Methantheline side effects

Percentages show how often each reaction appears relative to total reports for methantheline.

1
Dyspnoea9.3%4
2
Fatigue7.0%3
3
Death7.0%3
4
Fluid Retention7.0%3
5
Abdominal Pain4.7%2
6
Hyperhidrosis4.7%2
7
Syncope4.7%2
8
Hyponatraemia4.7%2
9
Anaemia4.7%2
10
Arthralgia4.7%2
11
Cellulitis4.7%2
12
Confusional State4.7%2
13
Drug Abuser4.7%2
14
Muscle Spasms4.7%2
15
Oedema Peripheral4.7%2

These are voluntary reports and do not establish that methantheline caused these reactions.

Report severity

90.7%Serious39 reports
41.9%Hospitalizations18 reports
25.6%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Methantheline drug interactions

Other drugs that appear in adverse event reports alongside methantheline. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sildenafil-citrate39.5%17
2
Ambrisentan9.3%4
3
Epoprostenol-sodium9.3%4
4
Venlafaxine7.0%3
5
Bosentan7.0%3
6
Fluticasone4.7%2
7
Salmeterol-xinafoate4.7%2
8
Baclofen4.7%2
9
Carbamazepine4.7%2
10
Lamotrigine4.7%2
11
Metoprolol4.7%2
12
Telmisartan4.7%2
13
Medroxyprogesterone-acetate2.3%1
14
Oxycodone2.3%1
15
Acetaminophen2.3%1

Taken alongside

1
Furosemide18.6%8
2
Spironolactone14.0%6
3
Metformin14.0%6
4
Albuterol11.6%5
5
Atorvastatin-calcium11.6%5
6
Aspirin11.6%5
7
Pantoprazole-sodium9.3%4
8
Bosentan9.3%4
9
Ergocalciferol9.3%4
10
Amlodipine7.0%3
11
Carvedilol7.0%3
12
Duloxetine-hydrochloride7.0%3
13
Lansoprazole7.0%3
14
Insulin7.0%3
15
Sertraline-hydrochloride7.0%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports methantheline side effects

72.1% of methantheline adverse event reports involve female patients and 14.0% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female72.1%
Male14.0%
Unknown14.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6450.0%
65+50.0%

What is methantheline used for

Conditions and purposes for which patients were taking methantheline when the adverse event was reported.

Cor PulmonaleDrug Use For Unknown IndicationDepressionHyperhidrosisIll-defined DisorderMenopauseMicturition DisorderProduct Used For Unknown IndicationPulmonary Arterial HypertensionPulmonary HypertensionProduct Used For Unknown IndicationSalivary HypersecretionScleroderma

Methantheline brand names and reporting trend

Methantheline is sold under the brand name Banthine.

Brand names

Banthine26

Quarterly reports (20052025)

2005201020152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking methantheline with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.