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Metaraminol Side Effects

The most commonly reported side effects of metaraminol include respiratory failure, condition aggravated, and hypotension, based on 509 FDA adverse event reports from 2004 to 2025. 6.9% of reports found the drug to be ineffective.

Metaraminol side effects

Percentages show how often each reaction appears relative to total reports for metaraminol.

1
Respiratory Failure10.2%52
2
Condition Aggravated8.8%45
3
Hypotension7.7%39
4
Anaphylactic Reaction6.9%35
5
Drug Ineffective6.9%35
6
Acute Kidney Injury6.1%31
7
Cardiac Arrest4.3%22
8
Pneumonia4.3%22
9
Pulmonary Embolism4.1%21
10
Rash3.7%19
11
Angioedema2.9%15
12
Stress Cardiomyopathy2.9%15
13
Multiple Organ Dysfunction Syndrome2.9%15
14
Overdose2.8%14
15
Vomiting2.6%13

These are voluntary reports and do not establish that metaraminol caused these reactions.

Report severity

97.2%Serious495 reports
46.8%Hospitalizations238 reports
14.5%Fatal74 reports

Seriousness is determined by the reporter, not by OpenClaim.

Metaraminol drug interactions

Other drugs that appear in adverse event reports alongside metaraminol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Propofol25.1%128
2
Fentanyl20.8%106
3
Rocuronium-bromide15.9%81
4
Midazolam14.3%73
5
Dexamethasone12.8%65
6
Vancomycin11.4%58
7
Hydrocortisone11.2%57
8
Sodium-chloride10.8%55
9
Magnesium-sulfate10.4%53
10
Epinephrine10.0%51
11
Potassium-chloride9.8%50
12
Albuterol9.4%48
13
Omeprazole9.2%47
14
Acetaminophen9.0%46
15
Metoclopramide-hydrochloride8.4%43

Taken alongside

1
Propofol26.7%136
2
Acetaminophen24.4%124
3
Fentanyl19.8%101
4
Ondansetron17.9%91
5
Midazolam16.9%86
6
Furosemide15.3%78
7
Apomorphine-hydrochloride13.9%71
8
Omeprazole13.6%69
9
Potassium-chloride13.4%68
10
Epinephrine13.0%66
11
Dexamethasone12.4%63
12
Metoclopramide-hydrochloride12.0%61
13
Hydrocortisone9.6%49
14
Meropenem9.2%47
15
Cyclizine-lactate9.0%46

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports metaraminol side effects

50.1% of metaraminol adverse event reports involve female patients and 40.1% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.1%
Male40.1%
Unknown9.8%

Age group

< 21.6%
2–112.5%
12–173.7%
18–6451.9%
65+40.3%

What is metaraminol used for

Conditions and purposes for which patients were taking metaraminol when the adverse event was reported.

AnaesthesiaAnaphylactic ReactionAnaphylactic ShockAntibiotic ProphylaxisAbscess DrainageAdverse EventAnaesthesiaBlood Pressure AbnormalBlood Pressure DecreasedBlood Pressure ManagementBlood Pressure MeasurementBlood Pressure DecreasedBlood Pressure IncreasedBlood Pressure ManagementBlood Pressure Measurement

Showing 15 of 69 indications

Metaraminol brand names and reporting trend

Metaraminol is sold under the brand name Aramine.

Brand names

Aramine498

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking metaraminol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.