OpenClaim

Mesoridazine Side Effects

The most commonly reported side effects of mesoridazine include insomnia, diabetes mellitus, and psychomotor hyperactivity, based on 40 FDA adverse event reports from 2004 to 2023. 7.5% of reports found the drug to be ineffective.

Mesoridazine side effects

Percentages show how often each reaction appears relative to total reports for mesoridazine.

1
Insomnia15.0%6
2
Diabetes Mellitus10.0%4
3
Psychomotor Hyperactivity7.5%3
4
Paranoia7.5%3
5
Tardive Dyskinesia7.5%3
6
Gait Disturbance7.5%3
7
Agitation7.5%3
8
Abdominal Pain Upper7.5%3
9
Constipation7.5%3
10
Electrocardiogram Abnormal7.5%3
11
Weight Decreased7.5%3
12
Drug Ineffective7.5%3
13
Schizophrenia5.0%2
14
Mental Disorder5.0%2
15
Drug Withdrawal Syndrome5.0%2

These are voluntary reports and do not establish that mesoridazine caused these reactions.

Report severity

82.5%Serious33 reports
45.0%Hospitalizations18 reports
7.5%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Mesoridazine drug interactions

Other drugs that appear in adverse event reports alongside mesoridazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Clozapine15.0%6
2
Quetiapine-fumarate12.5%5
3
Olanzapine10.0%4
4
Haloperidol5.0%2
5
Risperidone5.0%2
6
Nicotine5.0%2
7
Teduglutide5.0%2
8
Maprotiline-hydrochloride2.5%1
9
Chlorpromazine2.5%1
10
Fluoxetine-hydrochloride2.5%1
11
Paroxetine2.5%1
12
Clonazepam2.5%1
13
Diazepam2.5%1
14
Cyclosporine2.5%1
15
Oxaprozin2.5%1

Taken alongside

1
Lithium12.5%5
2
Hydroxyzine12.5%5
3
Atorvastatin-calcium12.5%5
4
Thioridazine12.5%5
5
Metformin12.5%5
6
Trazodone-hydrochloride10.0%4
7
Divalproex-sodium10.0%4
8
Omeprazole10.0%4
9
Mirtazapine10.0%4
10
Olanzapine10.0%4
11
Escitalopram-oxalate7.5%3
12
Lamotrigine7.5%3
13
Buspirone-hydrochloride7.5%3
14
Clonazepam7.5%3
15
Oxycodone7.5%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports mesoridazine side effects

45.0% of mesoridazine adverse event reports involve female patients and 55.0% involve male patients. The largest age group is adult at 88%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.0%
Male55.0%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6488.0%
65+12.0%

What is mesoridazine used for

Conditions and purposes for which patients were taking mesoridazine when the adverse event was reported.

AnxietyBipolar DisorderDelusionDementiaDepressionHallucinationMental DisorderMicrovillous Inclusion DiseaseProduct Used For Unknown IndicationPsychotic DisorderProduct Used For Unknown IndicationSchizoaffective DisorderSchizophrenia

Mesoridazine brand names and reporting trend

Mesoridazine is sold under the brand name Serentil.

Brand names

Serentil6

Quarterly reports (20042023)

20052020

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking mesoridazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.