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Meprobamate Side Effects

The most commonly reported side effects of meprobamate include toxicity to various agents, drug abuse, and drug toxicity, based on 3,259 FDA adverse event reports from 2004 to 2025. 2.1% of reports found the drug to be ineffective.

Meprobamate side effects

Percentages show how often each reaction appears relative to total reports for meprobamate.

1
Toxicity To Various Agents9.3%302
2
Drug Abuse4.6%150
3
Drug Toxicity3.2%104
4
Overdose3.0%98
5
Completed Suicide2.4%77
6
Pyrexia2.3%76
7
Fall2.3%74
8
Death2.2%72
9
Drug Ineffective2.1%69
10
Confusional State2.0%65
11
Dyspnoea2.0%65
12
Completed Suicide1.9%62
13
Off Label Use1.9%61
14
Pneumonia1.8%60
15
Malaise1.8%58

These are voluntary reports and do not establish that meprobamate caused these reactions.

Report severity

96.0%Serious3,130 reports
46.6%Hospitalizations1,519 reports
36.8%Fatal1,199 reports

Seriousness is determined by the reporter, not by OpenClaim.

Meprobamate drug interactions

Other drugs that appear in adverse event reports alongside meprobamate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Carisoprodol15.0%490
2
Acetaminophen10.0%325
3
Oxycodone9.3%304
4
Alprazolam6.9%226
5
Aspirin6.3%205
6
Hydrocodone5.7%185
7
Diazepam5.3%173
8
Diphenhydramine4.2%137
9
Hydroxyzine3.6%118
10
Clonazepam3.3%106
11
Tramadol-hydrochloride3.2%103
12
Methadone-hydrochloride3.1%100
13
Gabapentin2.9%96
14
Fentanyl2.9%94
15
Zolpidem-tartrate2.8%92

Taken alongside

1
Aspirin36.6%1,194
2
Furosemide8.8%287
3
Glimepiride8.2%266
4
Amlodipine6.9%226
5
Acetaminophen6.4%209
6
Esomeprazole5.3%173
7
Rosuvastatin5.0%163
8
Insulin4.9%161
9
Atorvastatin-calcium4.6%150
10
Prednisone3.9%128
11
Levothyroxine-sodium3.5%113
12
Metformin3.3%108
13
Lansoprazole3.2%103
14
Spironolactone3.1%102
15
Telmisartan2.9%96

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports meprobamate side effects

45.4% of meprobamate adverse event reports involve female patients and 47.4% involve male patients. The largest age group is elderly at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.4%
Male47.4%
Unknown7.2%

Age group

< 20.3%
2–110.3%
12–170.6%
18–6448.9%
65+49.8%

What is meprobamate used for

Conditions and purposes for which patients were taking meprobamate when the adverse event was reported.

Abnormal BehaviourAccidental ExposureAccidental OverdoseAccidental PoisoningAffective DisorderAggressionAgitationAgoraphobiaAlcohol AbuseAlcohol UseAlcohol Withdrawal SyndromeAlcoholismAnalgesic TherapyAnxietyAnxiolytic Therapy

Showing 15 of 100 indications

Meprobamate brand names and reporting trend

Meprobamate is sold under the brand name Tranmep.

Brand names

Tranmep1,338

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking meprobamate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.