OpenClaim

Meprednisone Side Effects

The most commonly reported side effects of meprednisone include pyrexia, foetal exposure during pregnancy, and off label use, based on 520 FDA adverse event reports from 2004 to 2025. 3.8% of reports found the drug to be ineffective.

Meprednisone side effects

Percentages show how often each reaction appears relative to total reports for meprednisone.

1
Pyrexia4.2%22
2
Foetal Exposure During Pregnancy4.2%22
3
Off Label Use4.2%22
4
Diarrhoea4.2%22
5
Pain4.0%21
6
Drug Ineffective3.8%20
7
Pneumonia3.7%19
8
Dyspnoea3.5%18
9
Oesophageal Atresia3.5%18
10
Urinary Tract Infection3.3%17
11
Premature Baby3.3%17
12
Low Birth Weight Baby2.9%15
13
Asthenia2.7%14
14
Febrile Neutropenia2.5%13
15
Death2.3%12

These are voluntary reports and do not establish that meprednisone caused these reactions.

Report severity

92.7%Serious482 reports
52.5%Hospitalizations273 reports
16.3%Fatal85 reports

Seriousness is determined by the reporter, not by OpenClaim.

Meprednisone drug interactions

Other drugs that appear in adverse event reports alongside meprednisone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Mycophenolate15.2%79
2
Tacrolimus10.2%53
3
Etanercept7.9%41
4
Methotrexate6.0%31
5
Cyclosporine4.0%21
6
Adalimumab3.8%20
7
Azathioprine3.7%19
8
Belatacept3.7%19
9
Rofecoxib3.3%17
10
Sirolimus2.9%15
11
Prednisone2.9%15
12
Certolizumab-pegol2.9%15
13
Rituximab2.7%14
14
Abatacept2.3%12
15
Enalapril-maleate2.3%12

Taken alongside

1
Methotrexate14.4%75
2
Folic-acid12.9%67
3
Omeprazole12.9%67
4
Levothyroxine-sodium8.3%43
5
Acetaminophen8.3%43
6
Mycophenolate7.9%41
7
Albuterol6.9%36
8
Prednisone6.2%32
9
Enalapril-maleate6.2%32
10
Sulfamethoxazole6.0%31
11
Ergocalciferol6.0%31
12
Furosemide5.8%30
13
Atorvastatin-calcium5.4%28
14
Losartan-potassium5.2%27
15
Metformin5.2%27

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports meprednisone side effects

56.2% of meprednisone adverse event reports involve female patients and 36.9% involve male patients. The largest age group is adult at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female56.2%
Male36.9%
Unknown6.9%

Age group

< 22.9%
2–113.7%
12–172.7%
18–6465.4%
65+25.2%

What is meprednisone used for

Conditions and purposes for which patients were taking meprednisone when the adverse event was reported.

Acne ConglobataAdrenal InsufficiencyArthritisAsthmaAsthmatic CrisisAutoimmune Haemolytic AnaemiaAcute Respiratory Distress SyndromeB-cell LymphomaBirdshot ChorioretinopathyBronchospasmBehcet^s SyndromeBronchitisCentral Nervous System LymphomaChronic Lymphocytic LeukaemiaChronic Obstructive Pulmonary Disease

Showing 15 of 91 indications

Meprednisone brand names and reporting trend

Meprednisone is sold under the brand name Betapar.

Brand names

Betapar659

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking meprednisone with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.