OpenClaim

Mepenzolate Side Effects

The most commonly reported side effects of mepenzolate include diarrhoea, hyperkalaemia, and abdominal pain, based on 58 FDA adverse event reports from 2004 to 2025.

Mepenzolate side effects

Percentages show how often each reaction appears relative to total reports for mepenzolate.

1
Diarrhoea6.9%4
2
Hyperkalaemia6.9%4
3
Abdominal Pain5.2%3
4
Fatigue5.2%3
5
Weight Increased5.2%3
6
Vascular Dementia5.2%3
7
Glomerulonephritis Chronic5.2%3
8
Constipation5.2%3
9
Pneumonia5.2%3
10
Pulmonary Toxicity5.2%3
11
Oedema Peripheral3.4%2
12
Adrenal Insufficiency3.4%2
13
Blood Glucose Decreased3.4%2
14
Dizziness3.4%2
15
Gait Disturbance3.4%2

These are voluntary reports and do not establish that mepenzolate caused these reactions.

Report severity

86.2%Serious50 reports
43.1%Hospitalizations25 reports
3.4%Fatal2 reports

Seriousness is determined by the reporter, not by OpenClaim.

Mepenzolate drug interactions

Other drugs that appear in adverse event reports alongside mepenzolate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab8.6%5
2
Lenvatinib-mesylate8.6%5
3
Pembrolizumab8.6%5
4
Axitinib8.6%5
5
Ibuprofen3.4%2
6
Fluvoxamine-maleate3.4%2
7
Rivaroxaban3.4%2
8
Mesalamine3.4%2
9
Denosumab3.4%2
10
Cannabidiol3.4%2
11
Bevacizumab3.4%2
12
Rosiglitazone-maleate1.7%1
13
Rifampin1.7%1
14
Levothyroxine-sodium1.7%1
15
Rofecoxib1.7%1

Taken alongside

1
Furosemide19.0%11
2
Acetaminophen13.8%8
3
Omeprazole13.8%8
4
Calcium13.8%8
5
Esomeprazole12.1%7
6
Metformin12.1%7
7
Isosorbide12.1%7
8
Atorvastatin-calcium10.3%6
9
Lansoprazole10.3%6
10
Desloratadine10.3%6
11
Montelukast-sodium8.6%5
12
Loratadine8.6%5
13
Aspirin8.6%5
14
Magnesium-oxide8.6%5
15
Candesartan-cilexetil8.6%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports mepenzolate side effects

34.5% of mepenzolate adverse event reports involve female patients and 55.2% involve male patients. The largest age group is elderly at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.5%
Male55.2%
Unknown10.3%

Age group

< 20.0%
2–112.0%
12–172.0%
18–6444.0%
65+52.0%

What is mepenzolate used for

Conditions and purposes for which patients were taking mepenzolate when the adverse event was reported.

Abdominal DistensionAbdominal DistensionAbdominal PainColitisColitis UlcerativeDiarrhoeaDiarrhoeaGastrointestinal DisorderIrritable Bowel SyndromeMyocardial IschaemiaProduct Used For Unknown IndicationProphylaxisProduct Used For Unknown Indication

Mepenzolate brand names and reporting trend

Mepenzolate is sold under the brand name Cantil.

Brand names

Cantil49

Quarterly reports (20042025)

2005201020202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking mepenzolate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.