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Menotropins Side Effects

The most commonly reported side effects of menotropins include ovarian hyperstimulation syndrome, abdominal distension, and injection site pain, based on 2,189 FDA adverse event reports from 2004 to 2025. 7.8% of reports found the drug to be ineffective.

Menotropins side effects

Percentages show how often each reaction appears relative to total reports for menotropins.

1
Ovarian Hyperstimulation Syndrome17.2%377
2
Drug Ineffective7.8%170
3
Abdominal Distension7.4%162
4
Injection Site Pain6.2%136
5
Nausea5.0%109
6
Headache5.0%109
7
Abdominal Pain4.7%102
8
Inappropriate Schedule Of Drug Administration3.7%82
9
Ascites3.7%81
10
Ovarian Hyperstimulation Syndrome3.6%79
11
Dyspnoea3.2%69
12
Fatigue2.5%55
13
Drug Exposure During Pregnancy2.4%53
14
Vomiting2.3%50
15
Abortion Spontaneous2.1%47

These are voluntary reports and do not establish that menotropins caused these reactions.

Report severity

50.3%Serious1,100 reports
29.1%Hospitalizations637 reports
1.6%Fatal36 reports

Seriousness is determined by the reporter, not by OpenClaim.

Menotropins drug interactions

Other drugs that appear in adverse event reports alongside menotropins. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Follitropin-alfa-beta33.9%743
2
Ganirelix-acetate16.2%354
3
Gonadotropin-chorionic14.8%323
4
Choriogonadotropin-alfa7.8%170
5
Progesterone5.5%120
6
Leuprolide5.3%115
7
Cetrorelix-acetate4.8%105
8
Urofollitropin3.3%73
9
Clomiphene-citrate3.2%71
10
Estradiol2.6%58
11
Letrozole1.8%40
12
Nafarelin-acetate1.8%39
13
Triptorelin-pamoate1.4%31
14
Ethinyl-estradiol0.9%20
15
Sterile0.9%19

Taken alongside

1
Ganirelix-acetate15.7%344
2
Progesterone13.9%304
3
Follitropin-alfa-beta13.8%301
4
Leuprolide12.3%269
5
Estradiol10.0%219
6
Azithromycin7.0%153
7
Gonadotropin-chorionic5.5%120
8
Choriogonadotropin-alfa5.4%118
9
Doxycycline4.8%106
10
Levothyroxine-sodium4.4%97
11
Sodium-chloride4.2%92
12
Ethinyl-estradiol3.7%80
13
Cetrorelix-acetate3.2%71
14
Letrozole3.2%71
15
Ergocalciferol3.2%69

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports menotropins side effects

90.0% of menotropins adverse event reports involve female patients and 1.6% involve male patients. The largest age group is adult at 98%. These figures reflect who reports side effects, not underlying risk.

Sex

Female90.0%
Male1.6%
Unknown8.4%

Age group

< 20.8%
2–11<0.1%
12–170.2%
18–6498.4%
65+0.5%

What is menotropins used for

Conditions and purposes for which patients were taking menotropins when the adverse event was reported.

Analgesic TherapyAnovulatory CycleArtificial InseminationArtificial Insemination By PartnerAssisted FertilisationAssisted Reproductive TechnologyAzoospermiaAdrenogenital SyndromeAnovulatory CycleArtificial InseminationAssisted FertilisationAssisted Reproductive TechnologyBlood Follicle Stimulating HormoneBreast Cancer FemaleBreast Cancer Female

Showing 15 of 65 indications

Menotropins brand names and reporting trend

Menotropins is sold under the brand name Pergonal.

Brand names

Pergonal589

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking menotropins with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.