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Menadiol Side Effects

The most commonly reported side effects of menadiol include butterfly rash, systemic lupus erythematosus, and drug hypersensitivity, based on 74 FDA adverse event reports from 2004 to 2024.

Menadiol side effects

Percentages show how often each reaction appears relative to total reports for menadiol.

1
Butterfly Rash17.6%13
2
Systemic Lupus Erythematosus17.6%13
3
Drug Hypersensitivity16.2%12
4
Fungal Infection16.2%12
5
Lupus-like Syndrome14.9%11
6
Arthritis14.9%11
7
Mood Swings14.9%11
8
Emotional Disorder14.9%11
9
Crying14.9%11
10
Disturbance In Social Behaviour14.9%11
11
Vascular Device Infection13.5%10
12
Personality Change13.5%10
13
Irritability13.5%10
14
Mood Altered13.5%10
15
Infective Pulmonary Exacerbation Of Cystic Fibrosis9.5%7

These are voluntary reports and do not establish that menadiol caused these reactions.

Report severity

97.3%Serious72 reports
71.6%Hospitalizations53 reports
4.1%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Menadiol drug interactions

Other drugs that appear in adverse event reports alongside menadiol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ivacaftor43.2%32
2
Lumacaftor17.6%13
3
Linezolid17.6%13
4
Omeprazole16.2%12
5
Tobramycin14.9%11
6
Meropenem6.8%5
7
Minocycline-hydrochloride6.8%5
8
Azithromycin6.8%5
9
Colistin-sulfate5.4%4
10
Piperacillin4.1%3
11
Tazobactam-sodium4.1%3
12
Pentazocine4.1%3
13
Fluoxetine-hydrochloride4.1%3
14
Fingolimod2.7%2
15
Itraconazole2.7%2

Taken alongside

1
Lipase67.6%50
2
Pancrelipase-amylase67.6%50
3
Protease67.6%50
4
Omeprazole59.5%44
5
Albuterol45.9%34
6
Sodium-chloride40.5%30
7
Ergocalciferol36.5%27
8
Vitamin-e33.8%25
9
Azithromycin32.4%24
10
Cholecalciferol32.4%24
11
Dornase-alfa28.4%21
12
Insulin28.4%21
13
Amikacin-sulfate28.4%21
14
Deoxycholic-acid20.3%15
15
Vitamin-a20.3%15

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports menadiol side effects

67.6% of menadiol adverse event reports involve female patients and 25.7% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female67.6%
Male25.7%
Unknown6.8%

Age group

< 21.6%
2–1124.2%
12–1722.6%
18–6450.0%
65+1.6%

What is menadiol used for

Conditions and purposes for which patients were taking menadiol when the adverse event was reported.

Cystic FibrosisDiabetes MellitusDrug Use For Unknown IndicationEpilepsyProduct Used For Unknown IndicationProduct Used For Unknown IndicationUpper Gastrointestinal HaemorrhageVitamin K Deficiency

Menadiol brand names and reporting trend

Menadiol is sold under the brand name Kappadione.

Brand names

Kappadione72

Quarterly reports (20042024)

20042024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking menadiol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.