OpenClaim

Meglumine Side Effects

The most commonly reported side effects of meglumine include off label use, pain, and joint swelling, based on 1,005 FDA adverse event reports from 2004 to 2025.

Meglumine side effects

Percentages show how often each reaction appears relative to total reports for meglumine.

1
Off Label Use45.7%459
2
Pain34.9%351
3
Joint Swelling34.2%344
4
Pemphigus33.9%341
5
General Physical Health Deterioration33.8%340
6
Hypertension33.5%337
7
Glossodynia33.5%337
8
Irritable Bowel Syndrome33.2%334
9
Folliculitis33.0%332
10
Inflammation33.0%332
11
Nail Disorder32.4%326
12
Rash32.3%325
13
Arthralgia32.2%324
14
Helicobacter Infection32.2%324
15
Type 2 Diabetes Mellitus32.2%324

These are voluntary reports and do not establish that meglumine caused these reactions.

Report severity

98.4%Serious989 reports
72.7%Hospitalizations731 reports
62.9%Fatal632 reports

Seriousness is determined by the reporter, not by OpenClaim.

Meglumine drug interactions

Other drugs that appear in adverse event reports alongside meglumine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Abatacept64.9%652
2
Adalimumab58.0%583
3
Diclofenac57.9%582
4
Methotrexate57.2%575
5
Etanercept57.2%575
6
Oxycodone57.2%575
7
Rituximab57.1%574
8
Prednisone56.9%572
9
Infliximab56.2%565
10
Leflunomide55.6%559
11
Naproxen55.4%557
12
Methylprednisolone55.0%553
13
Hydroxychloroquine-sulfate54.8%551
14
Alendronate-sodium54.7%550
15
Golimumab54.6%549

Taken alongside

1
Sulfasalazine20.6%207
2
Calcium19.1%192
3
Lorazepam18.3%184
4
Naproxen17.8%179
5
Secukinumab17.6%177
6
Quetiapine-fumarate16.8%169
7
Acetaminophen16.6%167
8
Lisinopril16.6%167
9
Pantoprazole-sodium16.3%164
10
Ibuprofen16.3%164
11
Risedronate-sodium15.8%159
12
Lansoprazole15.3%154
13
Cyanocobalamin15.1%152
14
Prednisolone14.3%144
15
Desogestrel14.3%144

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports meglumine side effects

65.8% of meglumine adverse event reports involve female patients and 17.2% involve male patients. The largest age group is adult at 85%. These figures reflect who reports side effects, not underlying risk.

Sex

Female65.8%
Male17.2%
Unknown17.0%

Age group

< 21.8%
2–110.4%
12–170.9%
18–6485.3%
65+11.6%

What is meglumine used for

Conditions and purposes for which patients were taking meglumine when the adverse event was reported.

AmyloidosisAngiogramArteriogram CoronaryArthrogramArthropathyAtrial FibrillationAmyloidosisAnalgesic TherapyAntiemetic Supportive CareArrhythmiaBack PainBlood Cholesterol IncreasedBowel PreparationBronchial CarcinomaCardiac Amyloidosis

Showing 15 of 93 indications

Meglumine brand names and reporting trend

Meglumine is sold under brand names including Isopaque 280, Isopaque 440.

Brand names

Isopaque 2801,343
Isopaque 4405

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking meglumine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.