OpenClaim

Meclizine Side Effects

The most commonly reported side effects of meclizine include dizziness, fatigue, and nausea, based on 20,625 FDA adverse event reports from 2004 to 2025. 4.1% of reports found the drug to be ineffective.

Meclizine side effects

Percentages show how often each reaction appears relative to total reports for meclizine.

1
Dizziness7.8%1,613
2
Fatigue7.4%1,517
3
Nausea6.9%1,426
4
Diarrhoea5.6%1,147
5
Headache5.4%1,119
6
Fall5.1%1,059
7
Pain5.1%1,053
8
Chronic Kidney Disease4.6%948
9
Dyspnoea4.1%851
10
Drug Ineffective4.1%846
11
Asthenia3.9%806
12
Vomiting3.6%745
13
Off Label Use3.5%721
14
Acute Kidney Injury3.2%664
15
Renal Failure3.2%654

These are voluntary reports and do not establish that meclizine caused these reactions.

Report severity

62.2%Serious12,826 reports
31.0%Hospitalizations6,403 reports
8.8%Fatal1,812 reports

Seriousness is determined by the reporter, not by OpenClaim.

Meclizine drug interactions

Other drugs that appear in adverse event reports alongside meclizine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide5.5%1,125
2
Esomeprazole4.4%906
3
Omeprazole4.2%874
4
Sodium-oxybate3.7%757
5
Pantoprazole-sodium3.2%666
6
Adalimumab3.0%620
7
Lansoprazole2.6%544
8
Dimethyl2.2%453
9
Interferon2.1%443
10
Pregabalin1.7%356
11
Dalfampridine1.7%355
12
Dupilumab1.7%350
13
Treprostinil1.6%325
14
Etanercept1.4%296
15
Gabapentin1.4%281

Taken alongside

1
Acetaminophen29.0%5,972
2
Aspirin25.1%5,177
3
Ergocalciferol24.0%4,944
4
Gabapentin20.4%4,208
5
Levothyroxine-sodium20.3%4,186
6
Albuterol19.9%4,101
7
Omeprazole18.5%3,813
8
Atorvastatin-calcium17.0%3,498
9
Furosemide16.7%3,448
10
Fluticasone16.7%3,435
11
Ondansetron16.2%3,349
12
Metoprolol16.0%3,306
13
Amlodipine14.0%2,882
14
Lisinopril13.7%2,823
15
Hydrocodone12.7%2,626

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports meclizine side effects

70.2% of meclizine adverse event reports involve female patients and 24.4% involve male patients. The largest age group is elderly at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female70.2%
Male24.4%
Unknown5.3%

Age group

< 20.4%
2–11<0.1%
12–170.6%
18–6448.0%
65+51.0%

What is meclizine used for

Conditions and purposes for which patients were taking meclizine when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal PainAccidental OverdoseAcoustic NeuromaAdverse EventAkathisiaAntiallergic TherapyAntidiarrhoeal Supportive CareAntiemetic Supportive CareAnxietyAnxiety DisorderArthritisAstheniaAutoimmune Disorder

Showing 15 of 224 indications

Meclizine brand names and reporting trend

Meclizine is sold under the brand name Meclizine Hydrochloride.

Brand names

Meclizine Hydrochloride6

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking meclizine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.