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Mecamylamine Side Effects

The most commonly reported side effects of mecamylamine include abdominal distension, constipation, and alanine aminotransferase increased, based on 9 FDA adverse event reports from 2004 to 2025.

Mecamylamine side effects

Percentages show how often each reaction appears relative to total reports for mecamylamine.

1
Abdominal Distension22.2%2
2
Constipation22.2%2
3
Alanine Aminotransferase Increased11.1%1
4
Drug Interaction11.1%1
5
Influenza11.1%1
6
Retinal Vein Thrombosis11.1%1
7
Visual Disturbance11.1%1
8
Pancreatitis11.1%1
9
Liver Function Test Abnormal11.1%1
10
Off Label Use11.1%1
11
Hyperhidrosis11.1%1
12
Drug Hypersensitivity11.1%1
13
Neuropathy Peripheral11.1%1
14
Headache11.1%1
15
Inflammation11.1%1

These are voluntary reports and do not establish that mecamylamine caused these reactions.

Report severity

44.4%Serious4 reports
33.3%Hospitalizations3 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Mecamylamine drug interactions

Other drugs that appear in adverse event reports alongside mecamylamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aripiprazole11.1%1
2
Adalimumab11.1%1
3
Exenatide-synthetic11.1%1
4
Metformin11.1%1
5
Meclizine-hydrochloride11.1%1
6
Sulfamethoxazole11.1%1
7
Trimethoprim11.1%1
8
Acetaminophen11.1%1
9
Hydrocodone11.1%1
10
Amino-acids11.1%1
11
Calcium-acetate11.1%1
12
Glycerin11.1%1
13
Magnesium-acetate11.1%1
14
Phosphoric-acid11.1%1
15
Potassium-chloride11.1%1

Taken alongside

1
Folic-acid22.2%2
2
Aspirin22.2%2
3
Insulin22.2%2
4
Simvastatin22.2%2
5
Magnesium-acetate-tetrahydrate11.1%1
6
Buspirone-hydrochloride11.1%1
7
Clonazepam11.1%1
8
Clonidine11.1%1
9
Lamotrigine11.1%1
10
Topiramate11.1%1
11
Carvedilol11.1%1
12
Hydroxyzine11.1%1
13
Metformin11.1%1
14
Methotrexate11.1%1
15
Pantoprazole-sodium11.1%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports mecamylamine side effects

33.3% of mecamylamine adverse event reports involve female patients and 44.4% involve male patients. The largest age group is adult at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female33.3%
Male44.4%
Unknown22.2%

Age group

< 20.0%
2–1120.0%
12–170.0%
18–6460.0%
65+20.0%

What is mecamylamine used for

Conditions and purposes for which patients were taking mecamylamine when the adverse event was reported.

Drug Use For Unknown IndicationProduct Used For Unknown IndicationTic

Mecamylamine brand names and reporting trend

Mecamylamine is sold under the brand name Inversine.

Brand names

Inversine1

Quarterly reports (20042025)

200420202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking mecamylamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.