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Mazindol Side Effects

The most commonly reported side effects of mazindol include drug abuse, drug dependence, and liver disorder, based on 56 FDA adverse event reports from 2004 to 2025.

Mazindol side effects

Percentages show how often each reaction appears relative to total reports for mazindol.

1
Drug Abuse8.9%5
2
Drug Dependence7.1%4
3
Liver Disorder5.4%3
4
Nausea5.4%3
5
Insomnia5.4%3
6
Nightmare5.4%3
7
Fear5.4%3
8
Death5.4%3
9
Euphoric Mood5.4%3
10
Product Use In Unapproved Indication5.4%3
11
Aggression5.4%3
12
Retinal Haemorrhage3.6%2
13
Dyspnoea3.6%2
14
Pyrexia3.6%2
15
Tachycardia3.6%2

These are voluntary reports and do not establish that mazindol caused these reactions.

Report severity

94.6%Serious53 reports
48.2%Hospitalizations27 reports
8.9%Fatal5 reports

Seriousness is determined by the reporter, not by OpenClaim.

Mazindol drug interactions

Other drugs that appear in adverse event reports alongside mazindol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate12.5%7
2
Fluoxetine-hydrochloride8.9%5
3
Diethylpropion-hydrochloride5.4%3
4
Methylphenidate5.4%3
5
Caffeine3.6%2
6
Rizatriptan-benzoate3.6%2
7
Zolmitriptan3.6%2
8
Butalbital3.6%2
9
Aspirin3.6%2
10
Alprazolam3.6%2
11
Acetaminophen3.6%2
12
Eprosartan-mesylate3.6%2
13
Iocetamic-acid1.8%1
14
Taurursodiol1.8%1
15
Atorvastatin-calcium1.8%1

Taken alongside

1
Aspirin10.7%6
2
Venlafaxine7.1%4
3
Methylphenidate5.4%3
4
Modafinil5.4%3
5
Alprazolam5.4%3
6
Insulin5.4%3
7
Metformin5.4%3
8
Gabapentin5.4%3
9
Folic-acid5.4%3
10
Amlodipine5.4%3
11
Clomipramine-hydrochloride3.6%2
12
Pseudoephedrine3.6%2
13
Ibuprofen3.6%2
14
Duloxetine-hydrochloride3.6%2
15
Vancomycin3.6%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports mazindol side effects

55.4% of mazindol adverse event reports involve female patients and 32.1% involve male patients. The largest age group is adult at 75%. These figures reflect who reports side effects, not underlying risk.

Sex

Female55.4%
Male32.1%
Unknown12.5%

Age group

< 20.0%
2–112.1%
12–176.3%
18–6475.0%
65+16.7%

What is mazindol used for

Conditions and purposes for which patients were taking mazindol when the adverse event was reported.

CataplexyCerebral InfarctionChronic Obstructive Pulmonary DiseaseDecreased AppetiteDrug AbuseEuphoric MoodEuphoric MoodNeck PainObesityOsteoarthritisObesityProduct Used For Unknown IndicationProduct Used For Unknown IndicationSomnolenceWeight Decreased

Showing 15 of 16 indications

Mazindol brand names and reporting trend

Mazindol is sold under the brand name Mazanor.

Brand names

Mazanor23

Quarterly reports (20042025)

2004200520152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking mazindol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.