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Marstacimab Side Effects

The most commonly reported side effects of marstacimab include haemarthrosis, haemorrhage, and epistaxis, based on 40 FDA adverse event reports from 2025 to 2025. 5.0% of reports found the drug to be ineffective.

Marstacimab side effects

Percentages show how often each reaction appears relative to total reports for marstacimab.

1
Haemarthrosis20.0%8
2
Haemorrhage15.0%6
3
Epistaxis7.5%3
4
Contusion7.5%3
5
Erectile Dysfunction5.0%2
6
Drug Ineffective5.0%2
7
Product Dose Omission Issue5.0%2
8
Fall5.0%2
9
Arthralgia5.0%2
10
Swelling5.0%2
11
Brain Fog5.0%2
12
Nephrolithiasis5.0%2
13
Alanine Aminotransferase Increased5.0%2
14
Aspartate Aminotransferase Increased5.0%2
15
Transient Ischaemic Attack5.0%2

These are voluntary reports and do not establish that marstacimab caused these reactions.

Report severity

60.0%Serious24 reports
27.5%Hospitalizations11 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Marstacimab drug interactions

Other drugs that appear in adverse event reports alongside marstacimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Emicizumab5.0%2

Taken alongside

1
Sodium-chloride5.0%2
2
Buspirone-hydrochloride2.5%1
3
Heparin2.5%1
4
Celecoxib2.5%1
5
Bictegravir2.5%1
6
Emtricitabine2.5%1
7
Tenofovir2.5%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports marstacimab side effects

7.5% of marstacimab adverse event reports involve female patients and 87.5% involve male patients. The largest age group is adult at 81%. These figures reflect who reports side effects, not underlying risk.

Sex

Female7.5%
Male87.5%
Unknown5.0%

Age group

< 20.0%
2–110.0%
12–1712.5%
18–6481.3%
65+6.3%

What is marstacimab used for

Conditions and purposes for which patients were taking marstacimab when the adverse event was reported.

Factor Ix DeficiencyFactor Viii DeficiencyHaemophiliaHaemophilia B Without Inhibitors

Marstacimab brand names and reporting trend

Marstacimab is sold under the brand name Hympavzi.

Brand names

Hympavzi3

Quarterly reports (20252025)

20252025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking marstacimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.