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Magnesium Sulfate Side Effects

The most commonly reported side effects of magnesium sulfate include vomiting, nausea, and off label use, based on 19,782 FDA adverse event reports from 2004 to 2025. 8.2% of reports found the drug to be ineffective.

Magnesium Sulfate side effects

Percentages show how often each reaction appears relative to total reports for magnesium sulfate.

1
Vomiting14.6%2,883
2
Nausea11.4%2,262
3
Drug Ineffective8.2%1,629
4
Off Label Use4.4%861
5
Abdominal Pain4.2%828
6
Headache4.2%826
7
Maternal Exposure During Pregnancy3.7%741
8
Pyrexia3.6%718
9
Foetal Exposure During Pregnancy3.5%695
10
Diarrhoea3.3%660
11
Premature Baby3.1%618
12
Abdominal Distension3.0%590
13
Pain2.9%569
14
Malaise2.7%544
15
Dyspnoea2.6%514

These are voluntary reports and do not establish that magnesium sulfate caused these reactions.

Report severity

67.5%Serious13,343 reports
37.5%Hospitalizations7,424 reports
11.8%Fatal2,338 reports

Seriousness is determined by the reporter, not by OpenClaim.

Magnesium Sulfate drug interactions

Other drugs that appear in adverse event reports alongside magnesium sulfate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-sulfate27.1%5,356
2
Potassium-sulfate18.9%3,735
3
Potassium-chloride13.4%2,643
4
Betamethasone5.6%1,109
5
Sodium-chloride4.7%939
6
Dextrose4.3%851
7
Azithromycin4.2%831
8
Acetaminophen4.1%802
9
Prednisone3.7%739
10
Dexamethasone3.2%636
11
Pantoprazole-sodium3.1%606
12
Calcium-chloride2.8%559
13
Amoxicillin2.8%558
14
Adalimumab2.8%554
15
Metronidazole2.8%550

Taken alongside

1
Potassium-chloride18.9%3,747
2
Acetaminophen18.5%3,659
3
Ondansetron13.5%2,680
4
Furosemide12.9%2,554
5
Sodium-chloride10.5%2,080
6
Pantoprazole-sodium10.1%1,989
7
Dexamethasone9.8%1,941
8
Aspirin9.5%1,882
9
Omeprazole8.3%1,642
10
Acyclovir7.9%1,567
11
Diphenhydramine7.8%1,545
12
Insulin7.8%1,541
13
Lorazepam7.5%1,484
14
Metoprolol7.4%1,470
15
Albuterol7.4%1,466

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports magnesium sulfate side effects

59.3% of magnesium sulfate adverse event reports involve female patients and 34.2% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.3%
Male34.2%
Unknown6.6%

Age group

< 24.2%
2–111.7%
12–171.4%
18–6453.0%
65+39.7%

What is magnesium sulfate used for

Conditions and purposes for which patients were taking magnesium sulfate when the adverse event was reported.

Abdominal DiscomfortAcute Coronary SyndromeAcute Kidney InjuryAcute Myocardial InfarctionAcute Respiratory Distress SyndromeAcute Respiratory FailureAdenocarcinoma Of ColonAdjuvant TherapyAdrenal InsufficiencyAdverse Drug ReactionAdverse EventAgitationAmniotic Cavity DisorderAnaemiaAnaesthesia

Showing 15 of 691 indications

Magnesium Sulfate brand names and reporting trend

Magnesium Sulfate is sold under the brand name Suflave.

Brand names

Suflave15,951

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking magnesium sulfate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.