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Lucinactant Side Effects

The most commonly reported side effects of lucinactant include medical device complication, pneumothorax, and economic problem, based on 19 FDA adverse event reports from 2010 to 2025.

Lucinactant side effects

Percentages show how often each reaction appears relative to total reports for lucinactant.

1
Medical Device Complication21.1%4
2
Pneumothorax21.1%4
3
Economic Problem10.5%2
4
Mitral Valve Incompetence10.5%2
5
Pleural Effusion10.5%2
6
Tricuspid Valve Incompetence10.5%2
7
Gastrooesophageal Reflux Disease10.5%2
8
Acute Respiratory Failure10.5%2
9
Pulmonary Haemorrhage10.5%2
10
Pulmonary Interstitial Emphysema Syndrome10.5%2
11
Product Use In Unapproved Indication10.5%2
12
Constipation10.5%2
13
Asthma5.3%1
14
Cardiac Failure5.3%1
15
Cardiomyopathy5.3%1

These are voluntary reports and do not establish that lucinactant caused these reactions.

Report severity

89.5%Serious17 reports
26.3%Hospitalizations5 reports
21.1%Fatal4 reports

Seriousness is determined by the reporter, not by OpenClaim.

Lucinactant drug interactions

Other drugs that appear in adverse event reports alongside lucinactant. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ivacaftor10.5%2
2
Digoxin5.3%1
3
Esomeprazole5.3%1
4
Metoclopramide-hydrochloride5.3%1
5
Insulin5.3%1
6
Enzalutamide5.3%1
7
Ibuprofen5.3%1
8
Acetaminophen5.3%1
9
Gentamicin-sulfate5.3%1
10
Indomethacin5.3%1
11
Elexacaftor-ivacaftor-tezacaftor5.3%1
12
Lactulose5.3%1
13
Tirzepatide5.3%1

Taken alongside

1
Ampicillin36.8%7
2
Potassium-chloride15.8%3
3
Furosemide15.8%3
4
Aspirin15.8%3
5
Ondansetron15.8%3
6
Levothyroxine-sodium15.8%3
7
Acetaminophen15.8%3
8
Amlodipine15.8%3
9
Albuterol15.8%3
10
Metformin15.8%3
11
Vitamin-a15.8%3
12
Gentamicin-sulfate15.8%3
13
Cefotaxime-sodium15.8%3
14
Vitamin-k15.8%3
15
Lisinopril10.5%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports lucinactant side effects

36.8% of lucinactant adverse event reports involve female patients and 52.6% involve male patients. The largest age group is neonate at 62%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.8%
Male52.6%
Unknown10.5%

Age group

< 261.5%
2–110.0%
12–170.0%
18–6423.1%
65+15.4%

What is lucinactant used for

Conditions and purposes for which patients were taking lucinactant when the adverse event was reported.

Food CravingNeonatal Respiratory Distress SyndromeProduct Used For Unknown IndicationRespiratory Distress

Lucinactant brand names and reporting trend

Lucinactant is sold under the brand name Surfaxin.

Brand names

Surfaxin3

Quarterly reports (20102025)

201020202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking lucinactant with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.