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Lorazepam Side Effects

The most commonly reported side effects of lorazepam include fatigue, nausea, and off label use, based on 182,371 FDA adverse event reports from 2004 to 2025. 6.1% of reports found the drug to be ineffective.

Lorazepam side effects

Percentages show how often each reaction appears relative to total reports for lorazepam.

1
Fatigue6.5%11,914
2
Drug Ineffective6.1%11,072
3
Nausea6.0%10,986
4
Off Label Use5.6%10,197
5
Diarrhoea4.9%8,906
6
Dyspnoea4.1%7,487
7
Headache4.0%7,321
8
Pain4.0%7,227
9
Anxiety3.9%7,100
10
Vomiting3.8%6,900
11
Dizziness3.6%6,551
12
Death3.3%6,004
13
Asthenia3.2%5,759
14
Malaise2.9%5,339
15
Fall2.9%5,241

These are voluntary reports and do not establish that lorazepam caused these reactions.

Report severity

77.1%Serious140,612 reports
41.6%Hospitalizations75,948 reports
14.2%Fatal25,906 reports

Seriousness is determined by the reporter, not by OpenClaim.

Lorazepam drug interactions

Other drugs that appear in adverse event reports alongside lorazepam. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Quetiapine-fumarate5.0%9,207
2
Lenalidomide4.1%7,416
3
Olanzapine3.4%6,270
4
Acetaminophen3.2%5,879
5
Adalimumab3.1%5,737
6
Oxycodone2.5%4,477
7
Rituximab2.4%4,450
8
Prednisone2.4%4,296
9
Pregabalin2.3%4,276
10
Risperidone2.3%4,225
11
Clozapine2.3%4,198
12
Aripiprazole2.3%4,148
13
Methotrexate2.1%3,750
14
Pantoprazole-sodium2.0%3,662
15
Infliximab1.9%3,533

Taken alongside

1
Acetaminophen20.7%37,822
2
Ondansetron12.2%22,290
3
Aspirin11.8%21,602
4
Ergocalciferol11.7%21,394
5
Levothyroxine-sodium11.2%20,436
6
Omeprazole10.9%19,800
7
Pantoprazole-sodium10.0%18,237
8
Albuterol9.9%17,973
9
Gabapentin9.3%16,877
10
Furosemide9.2%16,772
11
Oxycodone8.9%16,313
12
Dexamethasone8.3%15,046
13
Metoprolol7.5%13,692
14
Amlodipine7.5%13,657
15
Atorvastatin-calcium7.5%13,657

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports lorazepam side effects

60.0% of lorazepam adverse event reports involve female patients and 33.3% involve male patients. The largest age group is adult at 61%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.0%
Male33.3%
Unknown6.7%

Age group

< 20.9%
2–111.4%
12–172.2%
18–6461.0%
65+34.6%

What is lorazepam used for

Conditions and purposes for which patients were taking lorazepam when the adverse event was reported.

22q11.2 Deletion SyndromeAbdominal DiscomfortAbdominal PainAbdominal Pain UpperAbnormal BehaviourAbnormal DreamsAbortion SpontaneousAccidental ExposureAccidental Exposure To ProductAccidental Exposure To Product By ChildAccidental OverdoseAcute Lymphocytic LeukaemiaAcute PsychosisAcute Respiratory FailureAcute Stress Disorder

Showing 15 of 1,515 indications

Lorazepam brand names and reporting trend

Lorazepam is sold under the brand name Ativan.

Brand names

Ativan150,865

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking lorazepam with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.