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Liraglutide Side Effects

The most commonly reported side effects of liraglutide include nausea, blood glucose increased, and vomiting, based on 50,443 FDA adverse event reports from 2007 to 2025. 2.8% of reports found the drug to be ineffective.

Liraglutide side effects

Percentages show how often each reaction appears relative to total reports for liraglutide.

1
Nausea9.7%4,893
2
Blood Glucose Increased6.0%3,024
3
Vomiting5.4%2,738
4
Diarrhoea5.0%2,515
5
Nausea4.6%2,306
6
Pancreatitis3.5%1,788
7
Off Label Use3.5%1,751
8
Headache2.9%1,486
9
Fatigue2.8%1,435
10
Drug Ineffective2.8%1,397
11
Weight Decreased2.7%1,359
12
Decreased Appetite2.7%1,359
13
Dizziness2.5%1,258
14
Constipation2.3%1,174
15
Malaise2.2%1,127

These are voluntary reports and do not establish that liraglutide caused these reactions.

Report severity

49.3%Serious24,868 reports
23.1%Hospitalizations11,629 reports
3.8%Fatal1,901 reports

Seriousness is determined by the reporter, not by OpenClaim.

Liraglutide drug interactions

Other drugs that appear in adverse event reports alongside liraglutide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Insulin9.0%4,553
2
Metformin5.6%2,818
3
Exenatide-synthetic2.1%1,062
4
Sitagliptin1.6%795
5
Canagliflozin1.5%740
6
Empagliflozin1.2%593
7
Adalimumab1.0%526
8
Semaglutide1.0%506
9
Dulaglutide0.9%458
10
Hydrochlorothiazide0.9%429
11
Pantoprazole-sodium0.8%423
12
Omeprazole0.8%397
13
Dapagliflozin0.8%381
14
Furosemide0.7%370
15
Sodium-oxybate0.7%346

Taken alongside

1
Metformin18.7%9,447
2
Insulin15.4%7,750
3
Aspirin6.9%3,473
4
Atorvastatin-calcium6.6%3,326
5
Levothyroxine-sodium5.4%2,719
6
Lisinopril4.6%2,325
7
Ergocalciferol4.4%2,236
8
Furosemide4.1%2,067
9
Amlodipine4.1%2,060
10
Acetaminophen4.1%2,059
11
Hydrochlorothiazide3.8%1,895
12
Omeprazole3.7%1,886
13
Rosuvastatin3.7%1,844
14
Gabapentin3.5%1,788
15
Simvastatin3.5%1,779

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports liraglutide side effects

59.9% of liraglutide adverse event reports involve female patients and 34.3% involve male patients. The largest age group is adult at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.9%
Male34.3%
Unknown5.8%

Age group

< 20.1%
2–11<0.1%
12–170.3%
18–6466.1%
65+33.5%

What is liraglutide used for

Conditions and purposes for which patients were taking liraglutide when the adverse event was reported.

Abnormal Weight GainAccidental ExposureAcute Coronary SyndromeAdjuvant TherapyAdrenal NeoplasmAllergy TestAntiviral TreatmentAnxietyAppetite DisorderArthritisArthropathyAdverse Drug ReactionAdverse EventAntidiarrhoeal Supportive CareAnxiety

Showing 15 of 277 indications

Liraglutide brand names and reporting trend

Liraglutide is sold under the brand name Victoza.

Brand names

Victoza3,912

Quarterly reports (20072025)

20072010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking liraglutide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.