OpenClaim

Liotrix Side Effects

The most commonly reported side effects of liotrix include weight increased, loss of consciousness, and fatigue, based on 147 FDA adverse event reports from 2004 to 2025. 6.8% of reports found the drug to be ineffective.

Liotrix side effects

Percentages show how often each reaction appears relative to total reports for liotrix.

1
Weight Increased7.5%11
2
Loss Of Consciousness6.8%10
3
Drug Ineffective6.8%10
4
Fatigue6.1%9
5
Insomnia5.4%8
6
Hypertension5.4%8
7
Chest Pain4.8%7
8
Fall4.8%7
9
Blood Pressure Increased4.1%6
10
Dizziness4.1%6
11
Tremor4.1%6
12
Pharmaceutical Product Complaint4.1%6
13
Pain4.1%6
14
Cerebrovascular Accident4.1%6
15
Dyspnoea4.1%6

These are voluntary reports and do not establish that liotrix caused these reactions.

Report severity

76.2%Serious112 reports
44.2%Hospitalizations65 reports
7.5%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Liotrix drug interactions

Other drugs that appear in adverse event reports alongside liotrix. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
T316.3%24
2
Quetiapine-fumarate4.1%6
3
Insulin4.1%6
4
Rofecoxib3.4%5
5
Estropipate3.4%5
6
Paroxetine3.4%5
7
Levothyroxine-sodium3.4%5
8
Salmeterol-xinafoate2.7%4
9
Ethinyl-estradiol2.7%4
10
Medroxyprogesterone-acetate2.7%4
11
Pimozide2.7%4
12
Aspirin2.7%4
13
Valacyclovir-hydrochloride2.7%4
14
Acyclovir2.7%4
15
Phenytoin2.0%3

Taken alongside

1
T375.5%111
2
Acetaminophen13.6%20
3
Furosemide12.9%19
4
Aspirin12.2%18
5
Levothyroxine-sodium12.2%18
6
Hydrochlorothiazide9.5%14
7
Fluticasone8.2%12
8
Atorvastatin-calcium7.5%11
9
Tramadol-hydrochloride7.5%11
10
Montelukast-sodium7.5%11
11
Esomeprazole7.5%11
12
Pantoprazole-sodium6.8%10
13
Bupropion6.8%10
14
Estrogens6.8%10
15
Simvastatin6.8%10

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports liotrix side effects

85.0% of liotrix adverse event reports involve female patients and 10.2% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female85.0%
Male10.2%
Unknown4.8%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6458.9%
65+41.1%

What is liotrix used for

Conditions and purposes for which patients were taking liotrix when the adverse event was reported.

Autoimmune ThyroiditisDrug Use For Unknown IndicationHormone Replacement TherapyHyperthyroidismHypothyroidismProduct Used For Unknown IndicationProduct Used For Unknown IndicationThyroid DisorderThyroid NeoplasmThyroid Operation

Liotrix brand names and reporting trend

Liotrix is sold under the brand name Thyrolar-5.

Brand names

Thyrolar-514

Quarterly reports (20042025)

2005201020152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking liotrix with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.