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Levobunolol Side Effects

The most commonly reported side effects of levobunolol include treatment failure, diarrhoea, and fatigue, based on 717 FDA adverse event reports from 2004 to 2025. 3.1% of reports found the drug to be ineffective.

Levobunolol side effects

Percentages show how often each reaction appears relative to total reports for levobunolol.

1
Treatment Failure10.2%73
2
Diarrhoea4.5%32
3
Fatigue4.3%31
4
Asthenia3.5%25
5
Drug Ineffective3.1%22
6
Eye Irritation3.1%22
7
Nausea2.8%20
8
Hypersensitivity2.5%18
9
Vision Blurred2.4%17
10
Dizziness2.2%16
11
Headache2.2%16
12
Rash2.2%16
13
Nausea2.1%15
14
Dizziness2.1%15
15
Fall2.1%15

These are voluntary reports and do not establish that levobunolol caused these reactions.

Report severity

53.7%Serious385 reports
19.7%Hospitalizations141 reports
8.1%Fatal58 reports

Seriousness is determined by the reporter, not by OpenClaim.

Levobunolol drug interactions

Other drugs that appear in adverse event reports alongside levobunolol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Latanoprost10.2%73
2
Timolol8.4%60
3
Brimonidine-tartrate8.4%60
4
Dorzolamide-hydrochloride6.8%49
5
Lenalidomide6.3%45
6
Bimatoprost6.1%44
7
Travoprost5.2%37
8
Brinzolamide4.3%31
9
Ibuprofen2.8%20
10
Pilocarpine2.5%18
11
Calcium-chloride2.4%17
12
Magnesium-chloride2.4%17
13
Sodium-chloride2.4%17
14
Adalimumab2.1%15
15
Flurbiprofen2.1%15

Taken alongside

1
Aspirin18.4%132
2
Latanoprost18.3%131
3
Furosemide12.1%87
4
Atorvastatin-calcium11.3%81
5
Acetaminophen10.7%77
6
Amlodipine10.6%76
7
Levothyroxine-sodium10.3%74
8
Lisinopril9.5%68
9
Ergocalciferol9.2%66
10
Metoprolol8.6%62
11
Omeprazole8.5%61
12
Simvastatin8.4%60
13
Brimonidine-tartrate6.7%48
14
Hydrochlorothiazide6.4%46
15
Insulin6.0%43

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports levobunolol side effects

57.3% of levobunolol adverse event reports involve female patients and 37.5% involve male patients. The largest age group is elderly at 82%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.3%
Male37.5%
Unknown5.2%

Age group

< 20.0%
2–110.2%
12–170.0%
18–6418.0%
65+81.8%

What is levobunolol used for

Conditions and purposes for which patients were taking levobunolol when the adverse event was reported.

Abnormal Sensation In EyeAnalgesic TherapyAngle Closure GlaucomaAtrial FibrillationBlood PotassiumBlood Pressure MeasurementBorderline GlaucomaCataractCataract OperationDiabetes MellitusDrug Use For Unknown IndicationDevelopmental GlaucomaEye DisorderGlaucomaGlaucoma

Showing 15 of 28 indications

Levobunolol brand names and reporting trend

Levobunolol is sold under the brand name Betagan.

Brand names

Betagan4

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking levobunolol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.