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Levamisole Side Effects

The most commonly reported side effects of levamisole include toxicity to various agents, drug abuse, and drug use disorder, based on 711 FDA adverse event reports from 2004 to 2025.

Levamisole side effects

Percentages show how often each reaction appears relative to total reports for levamisole.

1
Toxicity To Various Agents37.7%268
2
Drug Abuse20.7%147
3
Drug Use Disorder10.4%74
4
Drug Interaction10.1%72
5
Substance Use Disorder9.6%68
6
Overdose8.9%63
7
Completed Suicide8.4%60
8
Intentional Product Misuse8.3%59
9
Death7.7%55
10
Adulterated Product5.6%40
11
Poisoning5.3%38
12
Coma5.3%38
13
Accidental Death5.2%37
14
Miosis5.1%36
15
Vomiting4.6%33

These are voluntary reports and do not establish that levamisole caused these reactions.

Report severity

99.3%Serious706 reports
25.2%Hospitalizations179 reports
57.1%Fatal406 reports

Seriousness is determined by the reporter, not by OpenClaim.

Levamisole drug interactions

Other drugs that appear in adverse event reports alongside levamisole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cocaine-hydrochloride53.0%377
2
Apomorphine-hydrochloride22.2%158
3
Lidocaine21.1%150
4
Acetaminophen18.7%133
5
Dihydrocodeine-bitartrate16.3%116
6
Hydroxyzine15.8%112
7
Diazepam15.5%110
8
Methadone-hydrochloride12.5%89
9
Pregabalin11.8%84
10
Alcohol11.4%81
11
Caffeine10.5%75
12
Fentanyl9.4%67
13
Theophylline9.1%65
14
Morphine-sulfate8.0%57
15
Nicotine6.9%49

Taken alongside

1
Acetaminophen2.5%18
2
Cocaine-hydrochloride2.3%16
3
Diazepam2.1%15
4
Caffeine1.8%13
5
Desogestrel1.3%9
6
Ethinyl-estradiol1.3%9
7
Mirtazapine1.3%9
8
Apomorphine-hydrochloride1.1%8
9
Nicotine1.1%8
10
Dihydrocodeine-bitartrate1.0%7
11
Lidocaine1.0%7
12
Sulfamethoxazole1.0%7
13
Cyclophosphamide0.8%6
14
Aspirin0.8%6
15
Gabapentin0.8%6

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports levamisole side effects

27.6% of levamisole adverse event reports involve female patients and 56.4% involve male patients. The largest age group is adult at 88%. These figures reflect who reports side effects, not underlying risk.

Sex

Female27.6%
Male56.4%
Unknown16.0%

Age group

< 21.0%
2–112.3%
12–173.8%
18–6488.5%
65+4.4%

What is levamisole used for

Conditions and purposes for which patients were taking levamisole when the adverse event was reported.

Accidental ExposureAccidental Exposure To ProductAdenocarcinomaAdenocarcinoma Of ColonAdjuvant TherapyAplastic AnaemiaAscariasisAdenocarcinoma Of ColonAnxietyBehcet^s SyndromeColon CancerColon Cancer MetastaticColorectal CancerDepressionDrug Abuse

Showing 15 of 44 indications

Levamisole brand names and reporting trend

Levamisole is sold under the brand name Ergamisol.

Brand names

Ergamisol757

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking levamisole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.