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Levacetylleucine Side Effects

The most commonly reported side effects of levacetylleucine include off label use, pneumonia, and fall, based on 700 FDA adverse event reports from 2004 to 2025.

Levacetylleucine side effects

Percentages show how often each reaction appears relative to total reports for levacetylleucine.

1
Off Label Use14.4%101
2
Pneumonia4.7%33
3
Fall4.3%30
4
Pyrexia4.1%29
5
Nausea3.9%27
6
Vomiting3.9%27
7
Anaemia3.0%21
8
Diarrhoea3.0%21
9
Acute Kidney Injury2.7%19
10
Product Use In Unapproved Indication2.7%19
11
Febrile Neutropenia2.6%18
12
Abdominal Pain2.0%14
13
Hepatitis1.9%13
14
Headache1.9%13
15
Agranulocytosis1.9%13

These are voluntary reports and do not establish that levacetylleucine caused these reactions.

Report severity

77.9%Serious545 reports
58.9%Hospitalizations412 reports
12.6%Fatal88 reports

Seriousness is determined by the reporter, not by OpenClaim.

Levacetylleucine drug interactions

Other drugs that appear in adverse event reports alongside levacetylleucine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Pembrolizumab3.4%24
2
Lansoprazole3.3%23
3
Aprepitant3.1%22
4
Fosaprepitant-dimeglumine3.1%22
5
Furosemide2.7%19
6
Trastuzumab2.6%18
7
Ramipril2.6%18
8
Acetaminophen2.4%17
9
Atezolizumab2.4%17
10
Pregabalin2.4%17
11
Paclitaxel2.3%16
12
Carboplatin2.3%16
13
Lenvatinib-mesylate2.3%16
14
Oxazepam2.3%16
15
Amoxicillin2.1%15

Taken alongside

1
Acetaminophen16.3%114
2
Furosemide14.0%98
3
Spironolactone8.1%57
4
Dexamethasone7.0%49
5
Oxycodone6.7%47
6
Insulin6.6%46
7
Omeprazole6.6%46
8
Tramadol-hydrochloride6.6%46
9
Lactulose6.4%45
10
Megestrol-acetate6.1%43
11
Amlodipine5.7%40
12
Potassium-chloride5.6%39
13
Pantoprazole-sodium5.4%38
14
Magnesium-oxide5.3%37
15
Esomeprazole5.3%37

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports levacetylleucine side effects

47.7% of levacetylleucine adverse event reports involve female patients and 45.1% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.7%
Male45.1%
Unknown7.1%

Age group

< 21.2%
2–119.9%
12–172.6%
18–6450.5%
65+35.8%

What is levacetylleucine used for

Conditions and purposes for which patients were taking levacetylleucine when the adverse event was reported.

Acute Hepatitis BAcute Kidney InjuryAdjuvant TherapyAlanine Aminotransferase IncreasedArgininosuccinate Synthetase DeficiencyAspartate AminotransferaseAspartate Aminotransferase IncreasedAtaxiaAtaxia TelangiectasiaAutoimmune HepatitisBlood Alkaline PhosphataseBlood Alkaline Phosphatase IncreasedBlood Bilirubin IncreasedBreast CancerBrain Neoplasm Benign

Showing 15 of 101 indications

Levacetylleucine brand names and reporting trend

Levacetylleucine is sold under the brand name Aqneursa.

Brand names

Aqneursa290

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking levacetylleucine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.