OpenClaim

Letibotulinumtoxina Side Effects

The most commonly reported side effects of letibotulinumtoxina include drug effect less than expected, therapy non-responder, and botulism, based on 144 FDA adverse event reports from 2024 to 2025. 10.4% of reports found the drug to be ineffective.

Letibotulinumtoxina side effects

Percentages show how often each reaction appears relative to total reports for letibotulinumtoxina.

1
Drug Effect Less Than Expected36.8%53
2
Therapy Non-responder31.3%45
3
Drug Ineffective10.4%15
4
Botulism6.9%10
5
Headache5.6%8
6
Chest Discomfort4.2%6
7
Dyspnoea3.5%5
8
Off Label Use3.5%5
9
Dysphagia3.5%5
10
Muscular Weakness3.5%5
11
Injection Site Pain3.5%5
12
Vision Blurred2.8%4
13
Dizziness2.8%4
14
Eyelid Ptosis2.8%4
15
Asthenia2.8%4

These are voluntary reports and do not establish that letibotulinumtoxina caused these reactions.

Report severity

14.6%Serious21 reports
9.7%Hospitalizations14 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Letibotulinumtoxina drug interactions

Other drugs that appear in adverse event reports alongside letibotulinumtoxina. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Onabotulinumtoxina1.4%2

Taken alongside

1
Abobotulinumtoxina2.1%3
2
Onabotulinumtoxina1.4%2
3
Tirzepatide1.4%2
4
Fexofenadine-hydrochloride0.7%1
5
Dexamethasone0.7%1
6
Ammonium0.7%1
7
Ascorbic-acid0.7%1
8
Epinephrine0.7%1
9
Prabotulinumtoxina-xvfs0.7%1
10
Levothyroxine-sodium0.7%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports letibotulinumtoxina side effects

91.0% of letibotulinumtoxina adverse event reports involve female patients and 4.9% involve male patients. The largest age group is adult at 97%. These figures reflect who reports side effects, not underlying risk.

Sex

Female91.0%
Male4.9%
Unknown4.2%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6496.9%
65+3.1%

What is letibotulinumtoxina used for

Conditions and purposes for which patients were taking letibotulinumtoxina when the adverse event was reported.

Face LiftFacial Cosmetic ProcedureOff Label UseProduct Use In Unapproved IndicationProduct Used For Unknown IndicationSkin Cosmetic ProcedureSkin Wrinkling

Letibotulinumtoxina brand names and reporting trend

Quarterly reports (20242025)

20242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking letibotulinumtoxina with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.