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Latanoprostene Side Effects

The most commonly reported side effects of latanoprostene include eye pain, eye irritation, and ocular hyperaemia, based on 1,035 FDA adverse event reports from 2004 to 2025. 5.3% of reports found the drug to be ineffective.

Latanoprostene side effects

Percentages show how often each reaction appears relative to total reports for latanoprostene.

1
Eye Pain10.0%104
2
Eye Irritation9.0%93
3
Ocular Hyperaemia7.1%74
4
Intraocular Pressure Increased5.6%58
5
Drug Ineffective5.3%55
6
Fatigue4.1%42
7
Vision Blurred4.1%42
8
Off Label Use4.1%42
9
Headache3.9%40
10
Death3.8%39
11
Visual Impairment3.6%37
12
Product Quality Issue3.3%34
13
Diarrhoea3.1%32
14
Dizziness3.1%32
15
Product Dose Omission Issue3.0%31

These are voluntary reports and do not establish that latanoprostene caused these reactions.

Report severity

38.5%Serious398 reports
11.8%Hospitalizations122 reports
5.6%Fatal58 reports

Seriousness is determined by the reporter, not by OpenClaim.

Latanoprostene drug interactions

Other drugs that appear in adverse event reports alongside latanoprostene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cenegermin-bkbj5.5%57
2
Latanoprost4.5%47
3
Brimonidine-tartrate4.4%46
4
Timolol3.6%37
5
Netarsudil3.4%35
6
Dorzolamide-hydrochloride2.9%30
7
Dupilumab2.3%24
8
Lenalidomide2.0%21
9
Doxycycline1.7%18
10
Brinzolamide1.4%15
11
Pimavanserin1.3%13
12
Adalimumab1.3%13
13
Bimatoprost1.1%11
14
Travoprost1.0%10
15
Treprostinil1.0%10

Taken alongside

1
Brimonidine-tartrate17.0%176
2
Timolol15.7%163
3
Amlodipine11.6%120
4
Aspirin11.0%114
5
Ergocalciferol10.1%105
6
Dorzolamide-hydrochloride9.8%101
7
Levothyroxine-sodium8.6%89
8
Atorvastatin-calcium8.0%83
9
Acetaminophen7.0%72
10
Albuterol6.6%68
11
Omeprazole6.5%67
12
Brinzolamide6.4%66
13
Metoprolol6.0%62
14
Calcium5.3%55
15
Fluticasone5.3%55

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports latanoprostene side effects

61.0% of latanoprostene adverse event reports involve female patients and 32.4% involve male patients. The largest age group is elderly at 77%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.0%
Male32.4%
Unknown6.7%

Age group

< 20.0%
2–110.2%
12–170.6%
18–6422.7%
65+76.5%

What is latanoprostene used for

Conditions and purposes for which patients were taking latanoprostene when the adverse event was reported.

Angle Closure GlaucomaAngle Closure GlaucomaBenign Prostatic HyperplasiaBlindnessBorderline GlaucomaCystoid Macular OedemaDiplopiaDry EyeEye DisorderExfoliation GlaucomaEye DisorderEye OperationGlaucomaGlaucomaGrowth Of Eyelashes

Showing 15 of 42 indications

Latanoprostene brand names and reporting trend

Latanoprostene is sold under the brand name Latanoprostene Bunod.

Brand names

Latanoprostene Bunod123

Quarterly reports (20042025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking latanoprostene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.