OpenClaim

Lasmiditan Side Effects

The most commonly reported side effects of lasmiditan include dizziness, feeling abnormal, and somnolence, based on 1,121 FDA adverse event reports from 2020 to 2025. 12.2% of reports found the drug to be ineffective.

Lasmiditan side effects

Percentages show how often each reaction appears relative to total reports for lasmiditan.

1
Dizziness18.6%209
2
Drug Ineffective12.2%137
3
Feeling Abnormal10.4%117
4
Somnolence9.5%107
5
Nausea7.4%83
6
Sedation7.2%81
7
Migraine7.0%78
8
Headache5.7%64
9
Fatigue5.7%64
10
Paraesthesia5.2%58
11
Hallucination3.9%44
12
Hypoaesthesia2.6%29
13
Serotonin Syndrome2.5%28
14
Insomnia2.5%28
15
Anxiety2.4%27

These are voluntary reports and do not establish that lasmiditan caused these reactions.

Report severity

16.5%Serious185 reports
4.8%Hospitalizations54 reports
1.2%Fatal13 reports

Seriousness is determined by the reporter, not by OpenClaim.

Lasmiditan drug interactions

Other drugs that appear in adverse event reports alongside lasmiditan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Galcanezumab-gnlm5.3%59
2
Eptinezumab-jjmr5.1%57
3
Onabotulinumtoxina1.5%17
4
Dupilumab1.3%15
5
Rimegepant1.1%12
6
Erenumab-aooe0.9%10
7
Fremanezumab-vfrm0.9%10
8
Sodium-oxybate0.8%9
9
Sumatriptan0.6%7
10
Treprostinil0.6%7
11
Ubrogepant0.5%6
12
Naratriptan-hydrochloride0.5%6
13
Calcium-oxybate0.5%6
14
Magnesium-oxybate0.5%6
15
Potassium-oxybate0.5%6

Taken alongside

1
Acetaminophen5.8%65
2
Onabotulinumtoxina5.3%59
3
Ondansetron5.2%58
4
Ubrogepant4.5%51
5
Rimegepant4.3%48
6
Topiramate4.2%47
7
Ergocalciferol4.2%47
8
Albuterol3.9%44
9
Levothyroxine-sodium3.4%38
10
Gabapentin3.2%36
11
Promethazine-hydrochloride2.9%33
12
Tizanidine-hydrochloride2.9%33
13
Galcanezumab-gnlm2.7%30
14
Famotidine2.7%30
15
Pantoprazole-sodium2.7%30

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports lasmiditan side effects

72.4% of lasmiditan adverse event reports involve female patients and 11.8% involve male patients. The largest age group is adult at 87%. These figures reflect who reports side effects, not underlying risk.

Sex

Female72.4%
Male11.8%
Unknown15.8%

Age group

< 20.2%
2–110.0%
12–170.4%
18–6486.5%
65+12.9%

What is lasmiditan used for

Conditions and purposes for which patients were taking lasmiditan when the adverse event was reported.

Cluster HeadacheCluster HeadacheDiabetes MellitusFacial PainHeadacheHereditary AngioedemaHeadacheHyperlipidaemiaHypertensionMigraineMigraine ProphylaxisMigraine Without AuraMaternal Exposure Timing UnspecifiedMigraineMigraine Prophylaxis

Showing 15 of 26 indications

Lasmiditan brand names and reporting trend

Lasmiditan is sold under brand names including Lasmiditan, Reyvow.

Brand names

Lasmiditan40
Reyvow7

Quarterly reports (20202025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking lasmiditan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.