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Lanreotide Side Effects

The most commonly reported side effects of lanreotide include off label use, diarrhoea, and death, based on 8,601 FDA adverse event reports from 2004 to 2025. 4.7% of reports found the drug to be ineffective.

Lanreotide side effects

Percentages show how often each reaction appears relative to total reports for lanreotide.

1
Off Label Use17.2%1,477
2
Diarrhoea17.1%1,475
3
Death13.5%1,161
4
Fatigue11.7%1,005
5
Nausea9.1%785
6
Abdominal Pain6.9%593
7
Injection Site Pain6.8%584
8
Headache6.3%545
9
Malaise5.3%458
10
Asthenia5.1%435
11
Weight Decreased5.1%435
12
Dizziness5.0%426
13
Pain4.9%425
14
Drug Ineffective4.7%408
15
Vomiting4.7%404

These are voluntary reports and do not establish that lanreotide caused these reactions.

Report severity

60.4%Serious5,197 reports
21.4%Hospitalizations1,837 reports
16.3%Fatal1,401 reports

Seriousness is determined by the reporter, not by OpenClaim.

Lanreotide drug interactions

Other drugs that appear in adverse event reports alongside lanreotide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Everolimus3.3%284
2
Octreotide-acetate3.3%283
3
Telotristat-etiprate2.9%251
4
Pegvisomant2.7%236
5
Lutetium1.7%142
6
Capecitabine1.3%116
7
Temozolomide1.0%89
8
Atorvastatin-calcium1.0%84
9
Duloxetine-hydrochloride1.0%82
10
Sunitinib-malate0.9%77
11
Levothyroxine-sodium0.7%64
12
Quetiapine-fumarate0.7%59
13
Alprazolam0.7%58
14
Metformin0.7%57
15
Alfuzosin-hydrochloride0.7%57

Taken alongside

1
Levothyroxine-sodium7.0%601
2
Ergocalciferol6.1%524
3
Amlodipine4.8%416
4
Metformin4.5%388
5
Aspirin4.0%346
6
Acetaminophen3.9%337
7
Octreotide-acetate3.6%306
8
Pantoprazole-sodium3.1%269
9
Atorvastatin-calcium2.9%249
10
Omeprazole2.8%244
11
Lipase2.7%233
12
Hydrochlorothiazide2.6%226
13
Pancrelipase-amylase2.5%217
14
Protease2.5%217
15
Metoprolol2.5%216

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports lanreotide side effects

52.1% of lanreotide adverse event reports involve female patients and 43.1% involve male patients. The largest age group is adult at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.1%
Male43.1%
Unknown4.8%

Age group

< 20.3%
2–110.5%
12–170.4%
18–6460.2%
65+38.6%

What is lanreotide used for

Conditions and purposes for which patients were taking lanreotide when the adverse event was reported.

Abdominal NeoplasmAcromegalyAdenocarcinomaAdenoma BenignAdrenal InsufficiencyAlbright^s DiseaseAnaemiaAngiodysplasiaAbdominal MassAbdominal PainAcral OvergrowthAcromegalyAdenoma BenignAdrenal DisorderAdrenal Gland Cancer

Showing 15 of 373 indications

Lanreotide brand names and reporting trend

Lanreotide is sold under the brand name Somatuline Depot.

Brand names

Somatuline Depot5,531

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking lanreotide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.