OpenClaim

L Side Effects

The most commonly reported side effects of l include sickle cell anaemia with crisis, product dose omission issue, and pain, based on 4,923 FDA adverse event reports from 2004 to 2025. 2.9% of reports found the drug to be ineffective.

L side effects

Percentages show how often each reaction appears relative to total reports for l.

1
Sickle Cell Anaemia With Crisis33.3%1,638
2
Product Dose Omission Issue13.4%661
3
Pain6.1%299
4
Nausea5.7%283
5
Product Dose Omission5.5%273
6
Headache4.8%237
7
Diarrhoea4.3%210
8
Hospitalisation3.8%189
9
Fatigue3.6%177
10
Abdominal Pain Upper3.5%172
11
Constipation3.3%164
12
Drug Ineffective2.9%144
13
Pain In Extremity2.8%139
14
Drug Dose Omission2.8%137
15
Back Pain2.7%134

These are voluntary reports and do not establish that l caused these reactions.

Report severity

61.9%Serious3,046 reports
37.8%Hospitalizations1,860 reports
3.3%Fatal162 reports

Seriousness is determined by the reporter, not by OpenClaim.

L drug interactions

Other drugs that appear in adverse event reports alongside l. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Voxelotor4.6%227
2
Lenalidomide2.1%102
3
Sodium-oxybate2.0%99
4
Adalimumab1.0%50
5
Pomalidomide0.9%45
6
Melphalan0.9%44
7
Teduglutide0.8%38
8
Paclitaxel0.7%35
9
Bevacizumab0.7%33
10
Niraparib-tosylate0.7%33
11
Carboplatin0.5%25
12
Capecitabine0.5%25
13
Gemcitabine0.5%24
14
Prednisone0.4%22
15
Busulfan0.4%21

Taken alongside

1
Folic-acid17.4%859
2
Hydroxyurea13.2%652
3
Ergocalciferol13.1%646
4
Acetaminophen10.1%499
5
Oxycodone9.0%443
6
Ibuprofen6.3%312
7
Aspirin5.7%281
8
Ondansetron5.3%259
9
Calcium5.2%258
10
Gabapentin4.9%243
11
Ascorbic-acid4.8%237
12
Cyanocobalamin4.7%230
13
Omeprazole4.2%208
14
Dexamethasone4.2%206
15
Albuterol4.1%203

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports l side effects

57.1% of l adverse event reports involve female patients and 40.1% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.1%
Male40.1%
Unknown2.8%

Age group

< 20.2%
2–1110.1%
12–1711.3%
18–6467.1%
65+11.3%

What is l used for

Conditions and purposes for which patients were taking l when the adverse event was reported.

Abdominal HerniaAlopeciaAmino Acid LevelAnaemiaAbdominal PainAbdominal Pain UpperAcute Chest SyndromeAmerican TrypanosomiasisAnaemiaArthritisBehcet^s SyndromeBlood DisorderBlood DisorderBlood Electrolytes AbnormalChronic Gastritis

Showing 15 of 146 indications

L brand names and reporting trend

L is sold under the brand name L-glutamine.

Brand names

L-glutamine1,436

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking l with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.