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Kanamycin Side Effects

The most commonly reported side effects of kanamycin include drug resistance, nausea, and vomiting, based on 706 FDA adverse event reports from 2004 to 2025. 2.7% of reports found the drug to be ineffective.

Kanamycin side effects

Percentages show how often each reaction appears relative to total reports for kanamycin.

1
Drug Resistance11.2%79
2
Nausea8.2%58
3
Vomiting7.4%52
4
Anaemia6.9%49
5
Neuropathy Peripheral6.1%43
6
Pyrexia4.7%33
7
Electrocardiogram Qt Prolonged4.5%32
8
Drug Reaction With Eosinophilia And Systemic Symptoms4.4%31
9
Treatment Failure4.4%31
10
Tuberculosis4.0%28
11
Off Label Use3.8%27
12
Arthralgia3.7%26
13
Diarrhoea3.5%25
14
Death3.3%23
15
Anxiety3.1%22

These are voluntary reports and do not establish that kanamycin caused these reactions.

Report severity

96.2%Serious679 reports
36.1%Hospitalizations255 reports
24.5%Fatal173 reports

Seriousness is determined by the reporter, not by OpenClaim.

Kanamycin drug interactions

Other drugs that appear in adverse event reports alongside kanamycin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Pyrazinamide29.0%205
2
Cycloserine26.8%189
3
Linezolid24.1%170
4
Ethambutol-hydrochloride22.7%160
5
Isoniazid20.0%141
6
Levofloxacin18.7%132
7
Clofazimine18.0%127
8
Ethionamide16.9%119
9
Bedaquiline-fumarate14.4%102
10
Moxifloxacin-hydrochloride13.0%92
11
Aminosalicylic10.9%77
12
Rifampin8.6%61
13
Streptomycin-sulfate7.5%53
14
Amikacin-sulfate6.7%47
15
Capreomycin-sulfate5.7%40

Taken alongside

1
Pyrazinamide18.1%128
2
Ethambutol-hydrochloride16.0%113
3
Ethionamide13.2%93
4
Furosemide10.9%77
5
Levofloxacin9.8%69
6
Isoniazid8.9%63
7
Cycloserine8.6%61
8
Pyridoxine8.1%57
9
Ofloxacin7.5%53
10
Spironolactone6.8%48
11
Moxifloxacin-hydrochloride6.5%46
12
Lactulose6.4%45
13
Aminosalicylic5.1%36
14
Linezolid4.2%30
15
Clarithromycin3.8%27

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports kanamycin side effects

45.8% of kanamycin adverse event reports involve female patients and 41.1% involve male patients. The largest age group is adult at 72%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.8%
Male41.1%
Unknown13.2%

Age group

< 20.8%
2–114.0%
12–173.2%
18–6472.3%
65+19.7%

What is kanamycin used for

Conditions and purposes for which patients were taking kanamycin when the adverse event was reported.

Alcoholic Liver DiseaseAmmonia AbnormalAntibiotic ProphylaxisAntibiotic TherapyAtypical Mycobacterial InfectionAtypical Mycobacterial InfectionBacteraemiaBacterial InfectionBone TuberculosisCholecystitisColorectal CancerColorectal Cancer MetastaticDisseminated TuberculosisDrug Use For Unknown IndicationExtrapulmonary Tuberculosis

Showing 15 of 62 indications

Kanamycin brand names and reporting trend

Kanamycin is sold under the brand name Klebcil.

Brand names

Klebcil77

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking kanamycin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.