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Ixabepilone Side Effects

The most commonly reported side effects of ixabepilone include fatigue, diarrhoea, and nausea, based on 1,906 FDA adverse event reports from 2004 to 2025.

Ixabepilone side effects

Percentages show how often each reaction appears relative to total reports for ixabepilone.

1
Fatigue5.4%103
2
Diarrhoea5.4%102
3
Nausea5.4%102
4
Vomiting5.2%100
5
Death4.4%84
6
Neutropenia4.3%82
7
Dehydration3.6%68
8
Neuropathy Peripheral3.6%68
9
Anaemia3.6%68
10
Febrile Neutropenia3.4%64
11
Death3.3%62
12
Fatigue3.1%59
13
Malignant Neoplasm Progression3.0%57
14
Nausea3.0%57
15
Malignant Neoplasm Progression2.9%55

These are voluntary reports and do not establish that ixabepilone caused these reactions.

Report severity

70.6%Serious1,346 reports
34.4%Hospitalizations656 reports
17.9%Fatal341 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ixabepilone drug interactions

Other drugs that appear in adverse event reports alongside ixabepilone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Capecitabine14.0%266
2
Bevacizumab10.5%201
3
Carboplatin10.4%199
4
Cyclophosphamide5.1%97
5
Trastuzumab4.7%90
6
Doxorubicin-hydrochloride3.6%68
7
Paclitaxel2.8%54
8
Gemcitabine2.8%53
9
Fulvestrant2.5%47
10
Docetaxel2.3%43
11
Vinorelbine-tartrate2.0%38
12
Fluorouracil1.9%36
13
Pegfilgrastim1.6%30
14
Epirubicin-hydrochloride1.5%28
15
Lapatinib-ditosylate1.4%27

Taken alongside

1
Diphenhydramine8.2%157
2
Dexamethasone8.1%154
3
Acetaminophen6.8%129
4
Ondansetron5.5%105
5
Oxycodone4.7%90
6
Ranitidine4.3%82
7
Prochlorperazine4.0%76
8
Hydrocodone3.6%68
9
Capecitabine3.6%68
10
Lorazepam3.0%58
11
Levothyroxine-sodium2.6%50
12
Palonosetron-hydrochloride2.6%50
13
Gabapentin2.3%44
14
Famotidine2.3%44
15
Zoledronic-acid2.3%43

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ixabepilone side effects

77.7% of ixabepilone adverse event reports involve female patients and 6.6% involve male patients. The largest age group is adult at 71%. These figures reflect who reports side effects, not underlying risk.

Sex

Female77.7%
Male6.6%
Unknown15.7%

Age group

< 20.0%
2–110.8%
12–17<0.1%
18–6470.9%
65+28.2%

What is ixabepilone used for

Conditions and purposes for which patients were taking ixabepilone when the adverse event was reported.

Adenocarcinoma Of The CervixAdenoid Cystic CarcinomaAgranulocytosisArthralgiaB-cell LymphomaBipolar Ii DisorderBladder CancerBreast CancerBreast Cancer FemaleBreast Cancer MaleBreast Cancer MetastaticBreast Cancer RecurrentBreast Cancer Stage IvBronchioloalveolar CarcinomaBreast Cancer

Showing 15 of 103 indications

Ixabepilone brand names and reporting trend

Ixabepilone is sold under the brand name Ixempra Kit.

Brand names

Ixempra Kit956

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ixabepilone with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.