OpenClaim

Isradipine Side Effects

The most commonly reported side effects of isradipine include nausea, oedema peripheral, and asthenia, based on 1,118 FDA adverse event reports from 2004 to 2025. 3.0% of reports found the drug to be ineffective.

Isradipine side effects

Percentages show how often each reaction appears relative to total reports for isradipine.

1
Nausea4.7%52
2
Oedema Peripheral3.8%43
3
Asthenia3.7%41
4
Hypertension3.0%34
5
Dyspnoea3.0%34
6
Drug Ineffective3.0%33
7
Headache2.9%32
8
Fatigue2.9%32
9
Drug Ineffective2.9%32
10
Acute Kidney Injury2.9%32
11
Off Label Use2.7%30
12
Dizziness2.6%29
13
Renal Failure2.6%29
14
Weight Decreased2.6%29
15
Chronic Kidney Disease2.6%29

These are voluntary reports and do not establish that isradipine caused these reactions.

Report severity

71.2%Serious796 reports
40.8%Hospitalizations456 reports
9.6%Fatal107 reports

Seriousness is determined by the reporter, not by OpenClaim.

Isradipine drug interactions

Other drugs that appear in adverse event reports alongside isradipine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Amlodipine3.8%43
2
Hydrochlorothiazide3.6%40
3
Mycophenolate3.1%35
4
Prednisone2.9%32
5
Tacrolimus2.4%27
6
Exenatide-synthetic2.3%26
7
Omeprazole2.3%26
8
Atorvastatin-calcium2.1%23
9
Levodopa2.1%23
10
Esomeprazole1.9%21
11
Metoprolol1.8%20
12
Adalimumab1.6%18
13
Cyclosporine1.6%18
14
Carbidopa1.6%18
15
Amoxicillin1.5%17

Taken alongside

1
Aspirin18.8%210
2
Hydrochlorothiazide15.6%174
3
Acetaminophen14.7%164
4
Furosemide13.4%150
5
Metoprolol11.0%123
6
Levothyroxine-sodium10.6%119
7
Atorvastatin-calcium10.6%118
8
Omeprazole9.7%108
9
Amlodipine9.5%106
10
Albuterol9.5%106
11
Metformin9.4%105
12
Ergocalciferol8.6%96
13
Lisinopril7.7%86
14
Simvastatin7.6%85
15
Prednisone7.2%80

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports isradipine side effects

58.1% of isradipine adverse event reports involve female patients and 36.8% involve male patients. The largest age group is elderly at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.1%
Male36.8%
Unknown5.1%

Age group

< 23.3%
2–114.5%
12–174.0%
18–6433.5%
65+54.7%

What is isradipine used for

Conditions and purposes for which patients were taking isradipine when the adverse event was reported.

ArrhythmiaBlood PressureBlood Pressure AbnormalBlood Pressure IncreasedBlood Pressure ManagementBlood Pressure MeasurementBlood Pressure Systolic IncreasedBlood Pressure AbnormalBlood Pressure MeasurementCardiac DisorderCoronary Artery DiseaseConnective Tissue DisorderDepressionDiabetes MellitusDrug Exposure During Pregnancy

Showing 15 of 43 indications

Isradipine brand names and reporting trend

Isradipine is sold under the brand name Isradipine.

Brand names

Isradipine621

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking isradipine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.