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Isosulfan Side Effects

The most commonly reported side effects of isosulfan include anaphylactic reaction, hypotension, and procedural complication, based on 123 FDA adverse event reports from 2004 to 2025.

Isosulfan side effects

Percentages show how often each reaction appears relative to total reports for isosulfan.

1
Anaphylactic Reaction25.2%31
2
Hypotension13.8%17
3
Procedural Complication7.3%9
4
Anaphylactic Reaction6.5%8
5
Hypotension6.5%8
6
Incorrect Route Of Drug Administration6.5%8
7
Skin Discolouration5.7%7
8
Rash5.7%7
9
Blood Pressure Decreased4.9%6
10
Skin Discolouration4.9%6
11
Drug Hypersensitivity4.9%6
12
Anaphylactic Shock4.1%5
13
Urticaria4.1%5
14
Pruritus4.1%5
15
Urticaria3.3%4

These are voluntary reports and do not establish that isosulfan caused these reactions.

Report severity

77.2%Serious95 reports
39.8%Hospitalizations49 reports
0.8%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Isosulfan drug interactions

Other drugs that appear in adverse event reports alongside isosulfan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Propofol4.1%5
2
Cefazolin-sodium3.3%4
3
Rocuronium-bromide3.3%4
4
Ketamine-hydrochloride2.4%3
5
Technetium-tc-99m-tilmanocept2.4%3
6
Fentanyl2.4%3
7
Lidocaine1.6%2
8
Sufentanil-citrate1.6%2
9
Midazolam1.6%2
10
Atracurium-besylate1.6%2
11
Dexamethasone1.6%2
12
Estradiol0.8%1
13
Potassium-phosphate-dibasic0.8%1
14
Potassium-phosphate-monobasic0.8%1
15
Sodium-phosphate0.8%1

Taken alongside

1
Fentanyl8.9%11
2
Propofol8.1%10
3
Midazolam6.5%8
4
Cefazolin-sodium5.7%7
5
Rocuronium-bromide4.9%6
6
Acetaminophen4.9%6
7
Aspirin4.9%6
8
Lidocaine4.1%5
9
Bupivacaine3.3%4
10
Esomeprazole3.3%4
11
Atorvastatin-calcium2.4%3
12
Hydrocodone2.4%3
13
Carvedilol2.4%3
14
Warfarin2.4%3
15
Lisinopril2.4%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports isosulfan side effects

79.7% of isosulfan adverse event reports involve female patients and 7.3% involve male patients. The largest age group is adult at 61%. These figures reflect who reports side effects, not underlying risk.

Sex

Female79.7%
Male7.3%
Unknown13.0%

Age group

< 20.0%
2–111.1%
12–171.1%
18–6461.4%
65+36.4%

What is isosulfan used for

Conditions and purposes for which patients were taking isosulfan when the adverse event was reported.

Biopsy BreastBiopsy Lymph GlandBladder DisorderBreast CancerBreast Conserving SurgeryDiagnostic ProcedureDrug Therapy EnhancementEndoscopy Small IntestineGeneral AnaesthesiaHysterectomyImaging ProcedureInvasive Ductal Breast CarcinomaLymphadenectomyLymphadenopathyLymphatic Disorder

Showing 15 of 34 indications

Isosulfan brand names and reporting trend

Isosulfan is sold under the brand name Isosulfan Blue.

Brand names

Isosulfan Blue88

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking isosulfan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.