OpenClaim

Isoproterenol Side Effects

The most commonly reported side effects of isoproterenol include toxic epidermal necrolysis, off label use, and torsade de pointes, based on 693 FDA adverse event reports from 2004 to 2025. 18.9% of reports found the drug to be ineffective.

Isoproterenol side effects

Percentages show how often each reaction appears relative to total reports for isoproterenol.

1
Drug Ineffective18.9%131
2
Toxic Epidermal Necrolysis7.1%49
3
Off Label Use6.6%46
4
Torsade De Pointes5.8%40
5
Ventricular Tachycardia4.8%33
6
Cardiogenic Shock3.6%25
7
Acute Kidney Injury3.6%25
8
Electrocardiogram Qt Prolonged3.6%25
9
Ventricular Fibrillation3.5%24
10
Cardiac Arrest3.2%22
11
Bradycardia3.2%22
12
Drug Interaction3.0%21
13
Death2.9%20
14
Overdose2.7%19
15
Toxicity To Various Agents2.7%19

These are voluntary reports and do not establish that isoproterenol caused these reactions.

Report severity

90.9%Serious630 reports
50.5%Hospitalizations350 reports
19.6%Fatal136 reports

Seriousness is determined by the reporter, not by OpenClaim.

Isoproterenol drug interactions

Other drugs that appear in adverse event reports alongside isoproterenol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Epinephrine16.5%114
2
Amiodarone-hydrochloride15.2%105
3
Lidocaine10.7%74
4
Methylprednisolone10.5%73
5
Midazolam8.9%62
6
Propofol8.8%61
7
Insulin8.4%58
8
Furosemide7.9%55
9
Loperamide-hydrochloride7.9%55
10
Lorazepam7.6%53
11
Diazepam7.2%50
12
Ipratropium-bromide7.1%49
13
Acetaminophen7.1%49
14
Sufentanil-citrate6.9%48
15
Enoxaparin-sodium6.9%48

Taken alongside

1
Amiodarone-hydrochloride10.7%74
2
Epinephrine10.4%72
3
Atorvastatin-calcium9.8%68
4
Furosemide8.2%57
5
Acetaminophen7.8%54
6
Aspirin7.5%52
7
Midazolam6.8%47
8
Metoprolol6.6%46
9
Sodium-bicarbonate6.3%44
10
Magnesium-acetate-tetrahydrate6.2%43
11
Insulin6.1%42
12
Levothyroxine-sodium5.8%40
13
Heparin5.5%38
14
Fentanyl5.5%38
15
Potassium-chloride5.3%37

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports isoproterenol side effects

42.1% of isoproterenol adverse event reports involve female patients and 47.8% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female42.1%
Male47.8%
Unknown10.1%

Age group

< 25.0%
2–113.6%
12–173.3%
18–6451.3%
65+36.7%

What is isoproterenol used for

Conditions and purposes for which patients were taking isoproterenol when the adverse event was reported.

Acute Myocardial InfarctionAdams-stokes SyndromeAngina PectorisArrhythmiaArrhythmia SupraventricularAsthmaAtrioventricular BlockAtrioventricular Block CompleteAtrioventricular Block Second DegreeAcidosisAcute Kidney InjuryArrhythmiaArrhythmia SupraventricularArrhythmic StormAtrial Fibrillation

Showing 15 of 128 indications

Isoproterenol brand names and reporting trend

Isoproterenol is sold under brand names including Aerolone, Medihaler-iso.

Brand names

Aerolone52
Medihaler-iso3

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking isoproterenol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.