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Ipratropium Side Effects

The most commonly reported side effects of ipratropium include dyspnoea, asthma, and pneumonia, based on 79,107 FDA adverse event reports from 2004 to 2025. 6.0% of reports found the drug to be ineffective.

Ipratropium side effects

Percentages show how often each reaction appears relative to total reports for ipratropium.

1
Dyspnoea13.2%10,403
2
Asthma6.7%5,321
3
Pneumonia6.1%4,861
4
Cough6.0%4,760
5
Drug Ineffective6.0%4,758
6
Off Label Use5.9%4,641
7
Wheezing4.4%3,479
8
Fatigue4.2%3,348
9
Chronic Obstructive Pulmonary Disease3.6%2,863
10
Nausea3.5%2,757
11
Headache3.1%2,445
12
Death3.1%2,427
13
Malaise3.1%2,418
14
Diarrhoea3.0%2,400
15
Product Quality Issue3.0%2,369

These are voluntary reports and do not establish that ipratropium caused these reactions.

Report severity

67.4%Serious53,314 reports
39.7%Hospitalizations31,404 reports
12.0%Fatal9,484 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ipratropium drug interactions

Other drugs that appear in adverse event reports alongside ipratropium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Albuterol22.3%17,665
2
Fluticasone6.7%5,290
3
Tiotropium-bromide6.6%5,196
4
Budesonide5.0%3,993
5
Salmeterol-xinafoate4.2%3,297
6
Prednisone3.6%2,882
7
Formoterol3.4%2,660
8
Omalizumab2.8%2,243
9
Montelukast-sodium2.8%2,216
10
Mepolizumab2.7%2,138
11
Dupilumab2.5%1,961
12
Acetaminophen2.3%1,793
13
Vilanterol-trifenatate2.2%1,775
14
Lenalidomide2.2%1,727
15
Omeprazole2.0%1,549

Taken alongside

1
Albuterol51.9%41,078
2
Fluticasone21.6%17,091
3
Acetaminophen18.8%14,889
4
Furosemide16.4%13,000
5
Aspirin15.7%12,452
6
Prednisone13.4%10,627
7
Omeprazole13.1%10,343
8
Budesonide12.8%10,125
9
Montelukast-sodium12.3%9,712
10
Ergocalciferol11.4%9,008
11
Salmeterol-xinafoate11.0%8,714
12
Levothyroxine-sodium11.0%8,708
13
Atorvastatin-calcium10.3%8,183
14
Pantoprazole-sodium9.7%7,711
15
Metoprolol9.6%7,607

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ipratropium side effects

55.5% of ipratropium adverse event reports involve female patients and 39.1% involve male patients. The largest age group is elderly at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female55.5%
Male39.1%
Unknown5.4%

Age group

< 20.8%
2–111.7%
12–170.9%
18–6442.9%
65+53.7%

What is ipratropium used for

Conditions and purposes for which patients were taking ipratropium when the adverse event was reported.

Abdominal PainAbdominal Pain UpperAcute Kidney InjuryAcute Myeloid LeukaemiaAcute Myocardial InfarctionAcute Pulmonary OedemaAcute Respiratory Distress SyndromeAcute Respiratory FailureAdenocarcinoma PancreasAdenoidal HypertrophyAdjuvant TherapyAdverse EventAffective DisorderAirway Secretion Clearance TherapyAlanine Aminotransferase Increased

Showing 15 of 746 indications

Ipratropium brand names and reporting trend

Ipratropium is sold under the brand name Combivent Respimat.

Brand names

Combivent Respimat30,535

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ipratropium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.