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Iohexol Side Effects

The most commonly reported side effects of iohexol include urticaria, pruritus, and dyspnoea, based on 9,035 FDA adverse event reports from 2004 to 2025.

Iohexol side effects

Percentages show how often each reaction appears relative to total reports for iohexol.

1
Urticaria10.7%969
2
Pruritus9.4%845
3
Dyspnoea8.1%728
4
Sneezing6.5%587
5
Erythema6.0%546
6
Nausea5.3%479
7
Vomiting4.9%444
8
Rash4.3%388
9
Chills3.6%321
10
Cough3.3%302
11
Anaphylactic Reaction3.2%286
12
Acute Kidney Injury3.0%268
13
Hypotension2.9%259
14
Contrast Media Reaction2.8%250
15
Pyrexia2.7%246

These are voluntary reports and do not establish that iohexol caused these reactions.

Report severity

81.9%Serious7,396 reports
34.7%Hospitalizations3,136 reports
7.2%Fatal647 reports

Seriousness is determined by the reporter, not by OpenClaim.

Iohexol drug interactions

Other drugs that appear in adverse event reports alongside iohexol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lidocaine1.6%147
2
Dexamethasone1.3%120
3
Methylprednisolone1.2%104
4
Omeprazole1.0%91
5
Aprotinin0.9%85
6
Vancomycin0.9%77
7
Pantoprazole-sodium0.8%76
8
Triamcinolone0.8%75
9
Amoxicillin0.8%75
10
Enoxaparin-sodium0.8%75
11
Furosemide0.8%71
12
Acetaminophen0.8%71
13
Midazolam0.8%70
14
Iodixanol0.7%66
15
Esomeprazole0.7%64

Taken alongside

1
Acetaminophen6.7%609
2
Aspirin5.1%461
3
Sodium-chloride5.0%454
4
Ondansetron4.8%435
5
Lidocaine4.4%397
6
Furosemide4.3%389
7
Heparin4.0%365
8
Atorvastatin-calcium3.4%306
9
Fentanyl3.3%299
10
Metoprolol3.2%290
11
Amlodipine3.1%279
12
Potassium-chloride3.0%272
13
Insulin3.0%272
14
Midazolam3.0%270
15
Pantoprazole-sodium2.9%264

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports iohexol side effects

46.0% of iohexol adverse event reports involve female patients and 36.0% involve male patients. The largest age group is adult at 61%. These figures reflect who reports side effects, not underlying risk.

Sex

Female46.0%
Male36.0%
Unknown18.1%

Age group

< 21.1%
2–110.7%
12–171.4%
18–6460.8%
65+36.0%

What is iohexol used for

Conditions and purposes for which patients were taking iohexol when the adverse event was reported.

Abdomen ScanAbdominal AbscessAbdominal DiscomfortAbdominal DistensionAbdominal ExplorationAbdominal HerniaAbdominal InjuryAbdominal MassAbdominal NeoplasmAbdominal PainAbdominal Pain LowerAbdominal Pain UpperAbdominal SepsisAbdominal SymptomAbdominal Tenderness

Showing 15 of 1,239 indications

Iohexol brand names and reporting trend

Iohexol is sold under the brand name Omnipaque 70.

Brand names

Omnipaque 701,195

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking iohexol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.