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Iodohippurate Side Effects

The most commonly reported side effects of iodohippurate include pain, malaise, and asthenia, based on 2,257 FDA adverse event reports from 2004 to 2025. 10.1% of reports found the drug to be ineffective.

Iodohippurate side effects

Percentages show how often each reaction appears relative to total reports for iodohippurate.

1
Pain13.7%310
2
Malaise12.8%290
3
Drug Ineffective10.1%227
4
Asthenia8.9%200
5
Weight Decreased8.8%199
6
Fatigue8.8%198
7
Pain In Extremity8.4%190
8
Headache7.9%179
9
Arthralgia7.7%174
10
Diarrhoea7.4%166
11
Dyspnoea7.3%165
12
Nausea7.3%165
13
Off Label Use7.2%162
14
Dizziness7.0%158
15
Gait Disturbance6.9%155

These are voluntary reports and do not establish that iodohippurate caused these reactions.

Report severity

97.0%Serious2,189 reports
41.8%Hospitalizations943 reports
6.5%Fatal146 reports

Seriousness is determined by the reporter, not by OpenClaim.

Iodohippurate drug interactions

Other drugs that appear in adverse event reports alongside iodohippurate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab9.0%204
2
Insulin4.7%106
3
Octreotide-acetate3.9%89
4
Abatacept3.9%87
5
Certolizumab-pegol3.4%77
6
Valsartan3.3%75
7
Etanercept3.1%69
8
Golimumab2.7%62
9
Hydrochlorothiazide2.6%59
10
Metformin2.3%53
11
Rosuvastatin2.3%51
12
Infliximab2.1%47
13
Tocilizumab1.9%42
14
Rivastigmine1.8%41
15
Atorvastatin-calcium1.6%36

Taken alongside

1
Losartan-potassium15.6%353
2
Omeprazole13.4%303
3
Simvastatin11.6%261
4
Prednisone10.2%231
5
Hydrochlorothiazide10.0%225
6
Metformin7.9%178
7
Methotrexate7.1%160
8
Atenolol7.0%157
9
Furosemide6.9%155
10
Pantoprazole-sodium6.6%150
11
Amlodipine6.2%141
12
Folic-acid5.8%130
13
Enalapril-maleate5.8%130
14
Rosuvastatin5.6%126
15
Ergocalciferol5.4%123

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports iodohippurate side effects

79.9% of iodohippurate adverse event reports involve female patients and 15.1% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female79.9%
Male15.1%
Unknown5.0%

Age group

< 20.2%
2–110.2%
12–170.5%
18–6453.7%
65+45.3%

What is iodohippurate used for

Conditions and purposes for which patients were taking iodohippurate when the adverse event was reported.

AngiopathyAutoimmune ThyroiditisAbdominal DiscomfortAnaemia ProphylaxisAutoimmune ThyroiditisBasedow^s DiseaseBlood Pressure AbnormalBlood Thyroid Stimulating HormoneBone DisorderBlood Pressure MeasurementBlood Thyroid Stimulating Hormone AbnormalCardiac DisorderCardiac DisorderDepressionDiuretic Therapy

Showing 15 of 80 indications

Iodohippurate brand names and reporting trend

Iodohippurate is sold under the brand name Hipputope.

Brand names

Hipputope6

Quarterly reports (20042025)

2004201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking iodohippurate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.