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Iodixanol Side Effects

The most commonly reported side effects of iodixanol include pruritus, rash, and erythema, based on 3,440 FDA adverse event reports from 2004 to 2025.

Iodixanol side effects

Percentages show how often each reaction appears relative to total reports for iodixanol.

1
Pruritus11.1%381
2
Rash7.4%255
3
Erythema6.5%225
4
Dyspnoea6.5%223
5
Urticaria6.1%210
6
Acute Kidney Injury3.8%131
7
Nausea3.8%130
8
Hypotension3.5%119
9
Vomiting3.3%114
10
Anaphylactic Reaction3.1%106
11
Contrast Media Allergy2.7%93
12
Rash Maculo-papular2.5%85
13
Acute Generalised Exanthematous Pustulosis2.4%84
14
Swelling Face2.4%83
15
Flushing2.4%82

These are voluntary reports and do not establish that iodixanol caused these reactions.

Report severity

90.9%Serious3,128 reports
40.4%Hospitalizations1,390 reports
7.9%Fatal273 reports

Seriousness is determined by the reporter, not by OpenClaim.

Iodixanol drug interactions

Other drugs that appear in adverse event reports alongside iodixanol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Heparin2.7%94
2
Amoxicillin2.0%68
3
Lidocaine1.9%64
4
Enoxaparin-sodium1.8%63
5
Iohexol1.7%60
6
Metformin1.7%59
7
Acetaminophen1.7%58
8
Aprotinin1.7%57
9
Atorvastatin-calcium1.6%55
10
Furosemide1.5%51
11
Verapamil-hydrochloride1.5%51
12
Pantoprazole-sodium1.5%50
13
Methylprednisolone1.4%49
14
Propofol1.4%48
15
Bisoprolol-fumarate1.3%46

Taken alongside

1
Aspirin7.8%269
2
Heparin6.8%234
3
Furosemide6.3%215
4
Acetaminophen5.1%176
5
Lidocaine4.4%152
6
Metoprolol4.1%142
7
Atorvastatin-calcium4.0%137
8
Clopidogrel-bisulfate3.6%125
9
Midazolam3.6%124
10
Gemfibrozil3.6%123
11
Pantoprazole-sodium3.5%121
12
Insulin3.5%121
13
Bisoprolol-fumarate3.5%121
14
Amlodipine3.3%115
15
Fentanyl3.1%108

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports iodixanol side effects

40.2% of iodixanol adverse event reports involve female patients and 43.2% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female40.2%
Male43.2%
Unknown16.6%

Age group

< 20.5%
2–110.7%
12–170.3%
18–6451.8%
65+46.6%

What is iodixanol used for

Conditions and purposes for which patients were taking iodixanol when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal HerniaAbdominal MassAbdominal NeoplasmAbdominal PainAbdominal Pain LowerAbdominal Pain UpperAbdominal Wall AbscessAbnormal Loss Of WeightAbscessAcute AbdomenAcute Coronary SyndromeAcute Myocardial InfarctionAdrenal Cyst

Showing 15 of 667 indications

Iodixanol brand names and reporting trend

Iodixanol is sold under the brand name Visipaque 320.

Brand names

Visipaque 320459

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking iodixanol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.