OpenClaim

Iobenguane Side Effects

The most commonly reported side effects of iobenguane include no adverse event, neutropenia, and mucosal inflammation, based on 228 FDA adverse event reports from 2004 to 2025. 10.5% of reports found the drug to be ineffective.

#1 Reported: No Adverse EventAll side effects ↓Top Co-Medication: MelphalanDrug interactions ↓41% of Reports Are ChildDemographics ↓

Iobenguane side effects

Percentages show how often each reaction appears relative to total reports for iobenguane.

1
No Adverse Event17.5%40
2
Neutropenia16.2%37
3
Mucosal Inflammation12.3%28
4
Drug Ineffective10.5%24
5
Radioisotope Scan Abnormal8.8%20
6
Thrombocytopenia5.7%13
7
Anaemia5.3%12
8
Disease Progression4.8%11
9
Product Use In Unapproved Indication4.8%11
10
Haematotoxicity3.9%9
11
Fatigue3.5%8
12
Febrile Neutropenia3.5%8
13
Platelet Count Decreased3.1%7
14
Nausea3.1%7
15
Hypertension2.6%6

These are voluntary reports and do not establish that iobenguane caused these reactions.

Report severity

67.5%Serious154 reports
19.7%Hospitalizations45 reports
12.3%Fatal28 reports

Seriousness is determined by the reporter, not by OpenClaim.

Iobenguane drug interactions

Other drugs that appear in adverse event reports alongside iobenguane. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Melphalan28.1%64
2
Etoposide9.6%22
3
Carboplatin7.5%17
4
Dinutuximab7.5%17
5
Topotecan-hydrochloride7.5%17
6
Vincristine-sulfate5.7%13
7
Cyclophosphamide5.3%12
8
Doxorubicin-hydrochloride4.8%11
9
Busulfan4.4%10
10
Cisplatin3.9%9
11
Irinotecan-hydrochloride2.6%6
12
Vorinostat2.2%5
13
Potassium-iodide2.2%5
14
Sargramostim1.8%4
15
Fludarabine-phosphate1.3%3

Taken alongside

1
Ondansetron21.1%48
2
Relugolix14.5%33
3
Liothyronine-sodium14.5%33
4
Potassium-iodide9.2%21
5
Ammonium4.8%11
6
Vincristine-sulfate3.5%8
7
Potassium-perchlorate3.5%8
8
Ursodiol3.5%8
9
Doxazosin-mesylate3.5%8
10
Cyclophosphamide3.1%7
11
Gabapentin3.1%7
12
Amlodipine2.6%6
13
Doxorubicin-hydrochloride2.6%6
14
Acetaminophen2.6%6
15
Sulfamethoxazole2.2%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports iobenguane side effects

43.9% of iobenguane adverse event reports involve female patients and 37.7% involve male patients. The largest age group is child at 41%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.9%
Male37.7%
Unknown18.4%

Age group

< 26.4%
2–1141.3%
12–1720.3%
18–6426.2%
65+5.8%

What is iobenguane used for

Conditions and purposes for which patients were taking iobenguane when the adverse event was reported.

Adrenal Gland CancerBenign Neoplasm Of Adrenal GlandBlood Catecholamines AbnormalBone Marrow Conditioning RegimenBone Marrow TransplantBone LesionComputerised Tomogram AbdomenDiagnostic ProcedureDiagnostic ProcedureFluid ReplacementGanglioneuroblastomaGanglioneuroblastomaInvestigationMediastinal MassMetastatic Neoplasm

Showing 15 of 41 indications

Iobenguane brand names and reporting trend

Iobenguane is sold under brand names including Iobenguane Sulfate I 131, Azedra.

Brand names

Iobenguane Sulfate I 13178
Azedra58

Quarterly reports (2004–2025)

2004201020202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking iobenguane with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

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