OpenClaim

Indinavir Side Effects

The most commonly reported side effects of indinavir include pain, emotional distress, and lipodystrophy acquired, based on 1,969 FDA adverse event reports from 2004 to 2025.

Indinavir side effects

Percentages show how often each reaction appears relative to total reports for indinavir.

1
Pain11.2%221
2
Emotional Distress11.2%220
3
Lipodystrophy Acquired10.6%209
4
Anxiety10.5%207
5
Anhedonia9.9%194
6
Eyelid Ptosis8.3%164
7
Mitochondrial Toxicity8.2%162
8
Diplopia8.2%161
9
Chronic Kidney Disease6.4%126
10
Osteoporosis5.5%108
11
Virologic Failure5.4%107
12
Drug Resistance5.3%104
13
Viral Mutation Identified5.1%101
14
Pathogen Resistance5.1%101
15
Osteopenia4.8%94

These are voluntary reports and do not establish that indinavir caused these reactions.

Report severity

94.2%Serious1,854 reports
28.7%Hospitalizations566 reports
6.0%Fatal119 reports

Seriousness is determined by the reporter, not by OpenClaim.

Indinavir drug interactions

Other drugs that appear in adverse event reports alongside indinavir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lamivudine51.8%1,019
2
Zidovudine45.3%892
3
Ritonavir41.6%820
4
Stavudine41.5%818
5
Tenofovir39.5%777
6
Didanosine32.1%633
7
Efavirenz29.5%581
8
Nevirapine25.5%502
9
Abacavir25.4%500
10
Saquinavir23.5%463
11
Lopinavir23.4%461
12
Emtricitabine20.9%411
13
Nelfinavir-mesylate19.0%375
14
Darunavir11.5%227
15
Enfuvirtide11.0%217

Taken alongside

1
Lamivudine22.9%451
2
Ritonavir18.6%366
3
Zidovudine17.2%339
4
Tenofovir12.4%244
5
Stavudine10.6%208
6
Emtricitabine10.4%204
7
Abacavir9.9%195
8
Didanosine9.5%187
9
Efavirenz8.5%168
10
Lopinavir7.7%152
11
Nelfinavir-mesylate7.3%144
12
Dolutegravir7.0%137
13
Sulfamethoxazole6.9%136
14
Raltegravir-potassium6.4%127
15
Atazanavir-sulfate6.4%126

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports indinavir side effects

24.5% of indinavir adverse event reports involve female patients and 62.4% involve male patients. The largest age group is adult at 86%. These figures reflect who reports side effects, not underlying risk.

Sex

Female24.5%
Male62.4%
Unknown13.2%

Age group

< 25.9%
2–111.5%
12–172.3%
18–6485.8%
65+4.6%

What is indinavir used for

Conditions and purposes for which patients were taking indinavir when the adverse event was reported.

Acquired Immunodeficiency SyndromeAcute Hiv InfectionAnti-infective TherapyAntifungal ProphylaxisAntiretroviral TherapyAntiviral ProphylaxisAntiviral TreatmentAcquired Immunodeficiency SyndromeAntiretroviral TherapyAntiviral ProphylaxisCachexiaCd4 Lymphocytes DecreasedChemotherapyChronic Hepatitis CChronic Hepatitis C

Showing 15 of 55 indications

Indinavir brand names and reporting trend

Indinavir is sold under the brand name Crixivan.

Brand names

Crixivan1,138

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking indinavir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.