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Indapamide Side Effects

The most commonly reported side effects of indapamide include hyponatraemia, acute kidney injury, and dyspnoea, based on 19,088 FDA adverse event reports from 2004 to 2025. 3.3% of reports found the drug to be ineffective.

Indapamide side effects

Percentages show how often each reaction appears relative to total reports for indapamide.

1
Hyponatraemia6.2%1,185
2
Acute Kidney Injury5.2%991
3
Dyspnoea4.5%856
4
Dizziness4.3%812
5
Nausea4.1%784
6
Diarrhoea4.1%779
7
Fatigue4.0%758
8
Drug Interaction3.6%681
9
Hypokalaemia3.5%665
10
Malaise3.4%650
11
Off Label Use3.4%644
12
Drug Ineffective3.3%632
13
Headache3.3%626
14
Vomiting3.3%621
15
Arthralgia3.1%594

These are voluntary reports and do not establish that indapamide caused these reactions.

Report severity

92.3%Serious17,617 reports
47.2%Hospitalizations9,014 reports
6.6%Fatal1,259 reports

Seriousness is determined by the reporter, not by OpenClaim.

Indapamide drug interactions

Other drugs that appear in adverse event reports alongside indapamide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Amlodipine7.5%1,440
2
Metformin6.3%1,212
3
Perindopril4.8%924
4
Atorvastatin-calcium4.3%819
5
Ramipril3.6%682
6
Omeprazole3.4%655
7
Bisoprolol-fumarate2.6%488
8
Aspirin2.4%451
9
Furosemide2.3%447
10
Rosuvastatin2.1%402
11
Apixaban2.1%402
12
Methotrexate2.0%387
13
Losartan-potassium1.9%371
14
Rituximab1.8%352
15
Valsartan1.8%350

Taken alongside

1
Amlodipine17.6%3,353
2
Atorvastatin-calcium15.8%3,015
3
Aspirin15.3%2,913
4
Metformin13.3%2,548
5
Acetaminophen10.6%2,027
6
Omeprazole10.0%1,916
7
Levothyroxine-sodium9.8%1,880
8
Bisoprolol-fumarate9.1%1,733
9
Perindopril9.0%1,711
10
Ramipril8.7%1,666
11
Simvastatin7.8%1,491
12
Losartan-potassium6.1%1,173
13
Albuterol6.0%1,138
14
Pantoprazole-sodium5.9%1,129
15
Rosuvastatin5.9%1,126

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports indapamide side effects

53.4% of indapamide adverse event reports involve female patients and 38.7% involve male patients. The largest age group is elderly at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.4%
Male38.7%
Unknown7.9%

Age group

< 20.3%
2–11<0.1%
12–17<0.1%
18–6435.5%
65+64.1%

What is indapamide used for

Conditions and purposes for which patients were taking indapamide when the adverse event was reported.

Accelerated HypertensionAccidental Exposure To Product By ChildAcute Coronary SyndromeAge Indeterminate Myocardial InfarctionAnaphylactic ReactionAntiinflammatory TherapyAnuriaArrhythmiaArteriosclerosis Coronary ArteryArthritisAsthmaAtrial FibrillationAccelerated HypertensionAcute Myocardial InfarctionAdverse Drug Reaction

Showing 15 of 249 indications

Indapamide brand names and reporting trend

Indapamide is sold under the brand name Indapamide.

Brand names

Indapamide19,485

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking indapamide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.