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Iloprost Side Effects

The most commonly reported side effects of iloprost include death, dyspnoea, and death, based on 10,710 FDA adverse event reports from 2004 to 2025.

Iloprost side effects

Percentages show how often each reaction appears relative to total reports for iloprost.

1
Death16.3%1,746
2
Dyspnoea10.7%1,146
3
Death6.6%702
4
Headache5.4%578
5
Pulmonary Arterial Hypertension4.6%492
6
Cough4.3%458
7
Fatigue4.2%452
8
Dizziness3.8%402
9
Pneumonia3.7%401
10
Nausea3.3%351
11
Pulmonary Hypertension3.2%346
12
Malaise3.0%324
13
Fluid Retention2.9%307
14
Hospitalisation2.9%307
15
Diarrhoea2.8%302

These are voluntary reports and do not establish that iloprost caused these reactions.

Report severity

86.4%Serious9,255 reports
47.3%Hospitalizations5,061 reports
40.3%Fatal4,319 reports

Seriousness is determined by the reporter, not by OpenClaim.

Iloprost drug interactions

Other drugs that appear in adverse event reports alongside iloprost. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bosentan16.4%1,752
2
Ambrisentan13.4%1,431
3
Macitentan6.2%668
4
Sildenafil-citrate4.4%475
5
Riociguat3.3%351
6
Treprostinil3.2%345
7
Selexipag1.8%194
8
Epoprostenol-sodium1.6%173
9
Tadalafil1.1%119
10
Warfarin0.7%75
11
Furosemide0.6%62
12
Rivaroxaban0.6%61
13
Digoxin0.5%54
14
Nitric-oxide0.4%47
15
Rituximab0.4%46

Taken alongside

1
Sildenafil-citrate24.8%2,657
2
Warfarin14.9%1,591
3
Furosemide11.1%1,185
4
Tadalafil9.2%983
5
Bosentan7.5%805
6
Oxygen7.3%778
7
Spironolactone6.2%662
8
Ambrisentan5.0%535
9
Aspirin4.9%522
10
Digoxin3.5%372
11
Levothyroxine-sodium3.3%354
12
Omeprazole3.2%342
13
Prednisone3.1%334
14
Acetaminophen3.1%327
15
Albuterol2.7%291

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports iloprost side effects

60.5% of iloprost adverse event reports involve female patients and 24.6% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.5%
Male24.6%
Unknown14.9%

Age group

< 21.9%
2–111.3%
12–171.1%
18–6453.5%
65+42.1%

What is iloprost used for

Conditions and purposes for which patients were taking iloprost when the adverse event was reported.

Accidental ExposureAcute Coronary SyndromeAcute Myeloid LeukaemiaAcute Respiratory Distress SyndromeAnkylosing SpondylitisAntineutrophil Cytoplasmic Antibody PositiveAntiphospholipid SyndromeAtrial Septal DefectAngiopathyAntiphospholipid SyndromeCardiac DisorderCardiac Failure CongestiveCardiac Septal DefectChronic Graft Versus Host DiseaseChronic Obstructive Pulmonary Disease

Showing 15 of 141 indications

Iloprost brand names and reporting trend

Iloprost is sold under the brand name Ventavis.

Brand names

Ventavis1,325

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking iloprost with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.