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Hydroxyamphetamine Side Effects

The most commonly reported side effects of hydroxyamphetamine include rash, diarrhoea, and pain, based on 261 FDA adverse event reports from 2004 to 2025. 5.4% of reports found the drug to be ineffective.

Hydroxyamphetamine side effects

Percentages show how often each reaction appears relative to total reports for hydroxyamphetamine.

1
Drug Ineffective5.4%14
2
Rash4.2%11
3
Diarrhoea3.8%10
4
Pain3.4%9
5
Fatigue3.4%9
6
Pneumonia3.4%9
7
Dyspnoea3.1%8
8
Death3.1%8
9
Fall3.1%8
10
Dyspnoea2.7%7
11
Pruritus2.7%7
12
Dizziness2.7%7
13
Nausea2.7%7
14
Drug Ineffective2.3%6
15
Off Label Use2.3%6

These are voluntary reports and do not establish that hydroxyamphetamine caused these reactions.

Report severity

55.9%Serious146 reports
28.0%Hospitalizations73 reports
7.7%Fatal20 reports

Seriousness is determined by the reporter, not by OpenClaim.

Hydroxyamphetamine drug interactions

Other drugs that appear in adverse event reports alongside hydroxyamphetamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tropicamide14.9%39
2
Dupilumab5.0%13
3
Adalimumab4.6%12
4
Apremilast3.8%10
5
Lenalidomide3.4%9
6
Budesonide3.1%8
7
Dimethyl2.7%7
8
Formoterol2.3%6
9
Clozapine1.5%4
10
Interferon1.5%4
11
Tiotropium-bromide1.5%4
12
Omeprazole1.5%4
13
Abatacept1.5%4
14
Fentanyl1.1%3
15
Albuterol1.1%3

Taken alongside

1
Albuterol19.9%52
2
Citalopram-hydrobromide14.9%39
3
Ergocalciferol14.9%39
4
Gabapentin13.4%35
5
Omeprazole13.0%34
6
Acetaminophen11.5%30
7
Prednisone10.3%27
8
Aspirin10.0%26
9
Fluticasone9.6%25
10
Lisinopril9.2%24
11
Furosemide9.2%24
12
Ipratropium-bromide9.2%24
13
Levothyroxine-sodium8.8%23
14
Folic-acid8.4%22
15
Montelukast-sodium7.7%20

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports hydroxyamphetamine side effects

61.3% of hydroxyamphetamine adverse event reports involve female patients and 31.0% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.3%
Male31.0%
Unknown7.7%

Age group

< 20.6%
2–111.1%
12–175.0%
18–6450.8%
65+42.5%

What is hydroxyamphetamine used for

Conditions and purposes for which patients were taking hydroxyamphetamine when the adverse event was reported.

AnxietyAsthmaBronchospasmChronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary DiseaseDepressionDiagnostic ProcedureDrug Use For Unknown IndicationEpilepsyEye DisorderHypersensitivityInhalation TherapyInsomniaLung DisorderLupus Nephritis

Showing 15 of 34 indications

Hydroxyamphetamine brand names and reporting trend

Hydroxyamphetamine is sold under the brand name Paredrine.

Brand names

Paredrine223

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking hydroxyamphetamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.