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Hydroflumethiazide Side Effects

The most commonly reported side effects of hydroflumethiazide include hypokalaemia, drug abuse, and erythema, based on 46 FDA adverse event reports from 2005 to 2025.

Hydroflumethiazide side effects

Percentages show how often each reaction appears relative to total reports for hydroflumethiazide.

1
Hypokalaemia17.4%8
2
Drug Abuse15.2%7
3
Erythema6.5%3
4
Back Pain6.5%3
5
Injection Site Pain4.3%2
6
Hypersensitivity4.3%2
7
Fall4.3%2
8
Anaemia4.3%2
9
Neutropenia4.3%2
10
Pruritus4.3%2
11
Flushing4.3%2
12
Myalgia4.3%2
13
Dyspnoea4.3%2
14
Arthralgia4.3%2
15
Death4.3%2

These are voluntary reports and do not establish that hydroflumethiazide caused these reactions.

Report severity

67.4%Serious31 reports
21.7%Hospitalizations10 reports
8.7%Fatal4 reports

Seriousness is determined by the reporter, not by OpenClaim.

Hydroflumethiazide drug interactions

Other drugs that appear in adverse event reports alongside hydroflumethiazide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Hydrochlorothiazide17.4%8
2
Gemcitabine6.5%3
3
Adalimumab4.3%2
4
Tiotropium-bromide4.3%2
5
Rituximab4.3%2
6
Pegfilgrastim4.3%2
7
Cyclophosphamide4.3%2
8
Vincristine-sulfate4.3%2
9
Prednisone4.3%2
10
Niacin4.3%2
11
Dabigatran-etexilate-mesylate4.3%2
12
Denosumab4.3%2
13
Spironolactone4.3%2
14
Enalapril-maleate4.3%2
15
Verapamil-hydrochloride4.3%2

Taken alongside

1
Reserpine60.9%28
2
Simvastatin17.4%8
3
Ergocalciferol17.4%8
4
Potassium-phosphate-monobasic17.4%8
5
Fish15.2%7
6
Aspirin15.2%7
7
Folic-acid13.0%6
8
Magnesium-acetate-tetrahydrate13.0%6
9
Calcium13.0%6
10
Ascorbic-acid13.0%6
11
Lisinopril13.0%6
12
Atorvastatin-calcium10.9%5
13
Omeprazole10.9%5
14
Cyanocobalamin10.9%5
15
Amlodipine8.7%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports hydroflumethiazide side effects

54.3% of hydroflumethiazide adverse event reports involve female patients and 39.1% involve male patients. The largest age group is elderly at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.3%
Male39.1%
Unknown6.5%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6445.5%
65+54.5%

What is hydroflumethiazide used for

Conditions and purposes for which patients were taking hydroflumethiazide when the adverse event was reported.

ArrhythmiaDiuretic TherapyDrug Use For Unknown IndicationEye DisorderHypertensionMacular DegenerationMedical DietProduct Used For Unknown IndicationSupplementation Therapy

Hydroflumethiazide brand names and reporting trend

Hydroflumethiazide is sold under the brand name Saluron.

Brand names

Saluron16

Quarterly reports (20052025)

200520152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking hydroflumethiazide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.