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Hydrocortamate Side Effects

The most commonly reported side effects of hydrocortamate include seizure, constipation, and product substitution issue, based on 14 FDA adverse event reports from 2012 to 2025. 35.7% of reports found the drug to be ineffective.

Hydrocortamate side effects

Percentages show how often each reaction appears relative to total reports for hydrocortamate.

1
Drug Ineffective35.7%5
2
Seizure28.6%4
3
Constipation14.3%2
4
Product Substitution Issue14.3%2
5
Discomfort14.3%2
6
Rash14.3%2
7
Sleep Disorder14.3%2
8
Product Substitution Issue7.1%1
9
Drug Ineffective7.1%1
10
Convulsion7.1%1
11
Blood Testosterone Decreased7.1%1
12
Malabsorption7.1%1
13
Coeliac Disease7.1%1
14
Vitamin D Decreased7.1%1
15
Blood Thyroid Stimulating Hormone Decreased7.1%1

These are voluntary reports and do not establish that hydrocortamate caused these reactions.

Report severity

64.3%Serious9 reports
21.4%Hospitalizations3 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Hydrocortamate drug interactions

Other drugs that appear in adverse event reports alongside hydrocortamate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Dupilumab28.6%4
2
Cannabidiol14.3%2
3
Lamotrigine7.1%1
4
Levothyroxine-sodium7.1%1
5
Testosterone7.1%1
6
Sunitinib-malate7.1%1
7
Vedolizumab7.1%1

Taken alongside

1
Phenytoin14.3%2
2
Midazolam14.3%2
3
Levetiracetam14.3%2
4
Potassium-citrate14.3%2
5
Thiamine14.3%2
6
Tacrolimus14.3%2
7
Clobetasol-propionate14.3%2
8
Lisinopril7.1%1
9
Aspirin7.1%1
10
Levothyroxine-sodium7.1%1
11
Atorvastatin-calcium7.1%1
12
Allopurinol7.1%1
13
Acetaminophen7.1%1
14
Hydrocodone7.1%1
15
Clonazepam7.1%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports hydrocortamate side effects

21.4% of hydrocortamate adverse event reports involve female patients and 50.0% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female21.4%
Male50.0%
Unknown28.6%

Age group

< 20.0%
2–1112.5%
12–1712.5%
18–6450.0%
65+25.0%

What is hydrocortamate used for

Conditions and purposes for which patients were taking hydrocortamate when the adverse event was reported.

EpilepsyInfantile SpasmsProduct Used For Unknown IndicationSeizure

Hydrocortamate brand names and reporting trend

Hydrocortamate is sold under the brand name Magnacort.

Brand names

Magnacort13

Quarterly reports (20122025)

201220162025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking hydrocortamate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.