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Homatropine Side Effects

The most commonly reported side effects of homatropine include nausea, fatigue, and diarrhoea, based on 743 FDA adverse event reports from 2004 to 2025.

Homatropine side effects

Percentages show how often each reaction appears relative to total reports for homatropine.

1
Nausea7.0%52
2
Fatigue6.3%47
3
Diarrhoea6.2%46
4
Death5.9%44
5
Dyspnoea5.8%43
6
Pneumonia5.4%40
7
Cough5.1%38
8
Vomiting4.8%36
9
Decreased Appetite4.4%33
10
Weight Decreased3.2%24
11
Asthenia3.1%23
12
Rash3.1%23
13
Headache3.1%23
14
Dyspnoea3.0%22
15
Pain3.0%22

These are voluntary reports and do not establish that homatropine caused these reactions.

Report severity

82.0%Serious609 reports
46.6%Hospitalizations346 reports
20.5%Fatal152 reports

Seriousness is determined by the reporter, not by OpenClaim.

Homatropine drug interactions

Other drugs that appear in adverse event reports alongside homatropine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bevacizumab13.9%103
2
Hydrocodone9.2%68
3
Irinotecan-hydrochloride7.4%55
4
Fluorouracil4.6%34
5
Capecitabine3.8%28
6
Lenalidomide3.1%23
7
Oxaliplatin2.4%18
8
Docetaxel2.0%15
9
Acetaminophen2.0%15
10
Sunitinib-malate2.0%15
11
Esomeprazole2.0%15
12
Nivolumab2.0%15
13
Oxycodone1.9%14
14
Erlotinib-hydrochloride1.9%14
15
Omeprazole1.9%14

Taken alongside

1
Hydrocodone53.4%397
2
Acetaminophen28.7%213
3
Albuterol21.5%160
4
Ondansetron17.6%131
5
Dexamethasone17.5%130
6
Aspirin17.1%127
7
Prednisone14.7%109
8
Furosemide14.0%104
9
Fluticasone13.9%103
10
Oxycodone13.3%99
11
Omeprazole12.2%91
12
Pantoprazole-sodium12.0%89
13
Levothyroxine-sodium11.7%87
14
Lorazepam11.6%86
15
Benzonatate11.0%82

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports homatropine side effects

51.0% of homatropine adverse event reports involve female patients and 43.9% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female51.0%
Male43.9%
Unknown5.1%

Age group

< 20.6%
2–111.9%
12–171.3%
18–6452.3%
65+43.9%

What is homatropine used for

Conditions and purposes for which patients were taking homatropine when the adverse event was reported.

Abdominal Pain UpperAcute Myocardial InfarctionAnaesthesiaAnaesthesia ProcedureArrhythmiaBradycardiaBronchitisCardiac ArrestCholinergic SyndromeColon CancerCoughChemotherapyCoughCrohn^s DiseaseDiarrhoea

Showing 15 of 51 indications

Homatropine brand names and reporting trend

Homatropine is sold under the brand name Homapin-5.

Brand names

Homapin-5344

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking homatropine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.