OpenClaim

Hexocyclium Side Effects

The most commonly reported side effects of hexocyclium include diarrhoea, acute kidney injury, and fatigue, based on 7,995 FDA adverse event reports from 2004 to 2025. 1.9% of reports found the drug to be ineffective.

Hexocyclium side effects

Percentages show how often each reaction appears relative to total reports for hexocyclium.

1
Diarrhoea3.7%299
2
Acute Kidney Injury3.1%251
3
Fatigue3.1%246
4
Nausea2.9%232
5
Vomiting2.7%214
6
Fall2.6%210
7
Dyspnoea2.6%204
8
Anaemia2.5%202
9
Pneumonia2.3%186
10
Off Label Use2.3%186
11
Pyrexia2.3%184
12
Asthenia2.3%184
13
Drug Interaction2.3%180
14
Dizziness2.2%179
15
Thrombocytopenia2.2%174

These are voluntary reports and do not establish that hexocyclium caused these reactions.

Report severity

91.4%Serious7,309 reports
57.0%Hospitalizations4,555 reports
12.0%Fatal963 reports

Seriousness is determined by the reporter, not by OpenClaim.

Hexocyclium drug interactions

Other drugs that appear in adverse event reports alongside hexocyclium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide3.3%260
2
Adalimumab2.8%224
3
Esomeprazole1.8%146
4
Prednisone1.8%143
5
Metformin1.7%139
6
Furosemide1.7%132
7
Dexamethasone1.6%129
8
Amoxicillin1.6%128
9
Acetaminophen1.6%128
10
Enoxaparin-sodium1.4%115
11
Tacrolimus1.4%111
12
Mycophenolate1.4%109
13
Warfarin1.4%108
14
Sulfamethoxazole1.3%107
15
Trimethoprim1.3%106

Taken alongside

1
Acetaminophen10.3%820
2
Aspirin9.3%742
3
Furosemide9.0%718
4
Omeprazole8.5%679
5
Prednisone7.3%582
6
Pantoprazole-sodium7.2%577
7
Levothyroxine-sodium6.8%546
8
Insulin6.8%542
9
Amlodipine6.2%499
10
Atorvastatin-calcium6.0%482
11
Metformin5.8%463
12
Ondansetron5.4%430
13
Ergocalciferol5.4%429
14
Esomeprazole5.0%400
15
Allopurinol4.4%353

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports hexocyclium side effects

34.9% of hexocyclium adverse event reports involve female patients and 59.8% involve male patients. The largest age group is elderly at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.9%
Male59.8%
Unknown5.3%

Age group

< 20.9%
2–111.2%
12–171.7%
18–6440.3%
65+56.0%

What is hexocyclium used for

Conditions and purposes for which patients were taking hexocyclium when the adverse event was reported.

Abdominal Pain UpperAbscess NeckAccidental ExposureAcneAcute Disseminated EncephalomyelitisAdjustment DisorderAdjustment Disorder With Disturbance Of ConductAdjustment Disorder With Mixed Anxiety And Depressed MoodAdjuvant TherapyAdverse EventAffect LabilityAffective DisorderAggressionAgitationAlanine Aminotransferase Increased

Showing 15 of 450 indications

Hexocyclium brand names and reporting trend

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking hexocyclium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.