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Hexachlorophene Side Effects

The most commonly reported side effects of hexachlorophene include death, nausea, and fatigue, based on 3,473 FDA adverse event reports from 2004 to 2025. 2.9% of reports found the drug to be ineffective.

Hexachlorophene side effects

Percentages show how often each reaction appears relative to total reports for hexachlorophene.

1
Death13.5%468
2
Nausea4.3%150
3
Fatigue3.5%122
4
Diarrhoea3.4%119
5
Muscle Spasms3.4%118
6
Hypotension3.4%117
7
Drug Ineffective2.9%101
8
Dizziness2.8%97
9
Peritonitis2.6%92
10
Therapeutic Product Effect Increased2.6%91
11
Pain2.6%89
12
Vomiting2.5%86
13
Dyspnoea2.4%85
14
Dehydration2.4%85
15
Headache2.3%81

These are voluntary reports and do not establish that hexachlorophene caused these reactions.

Report severity

72.8%Serious2,530 reports
32.9%Hospitalizations1,141 reports
23.8%Fatal827 reports

Seriousness is determined by the reporter, not by OpenClaim.

Hexachlorophene drug interactions

Other drugs that appear in adverse event reports alongside hexachlorophene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Icodextrin12.9%448
2
Dextrose6.2%217
3
Sodium-chloride5.8%201
4
Calcium-chloride3.7%129
5
Magnesium-chloride3.7%127
6
Sodium-lactate3.6%124
7
Patiromer-sorbitex-calcium2.7%94
8
Lenalidomide2.3%80
9
Adalimumab2.2%76
10
Chlorhexidine-gluconate1.4%50
11
Valacyclovir-hydrochloride1.2%41
12
Heparin1.2%41
13
Esomeprazole1.2%41
14
Alcohol1.2%41
15
Lidocaine1.2%40

Taken alongside

1
Aspirin12.5%433
2
Ergocalciferol9.5%331
3
Amlodipine9.2%318
4
Sevelamer9.2%318
5
Acetaminophen9.1%316
6
Insulin8.8%306
7
Atorvastatin-calcium7.3%252
8
Furosemide7.2%250
9
Gabapentin7.1%246
10
Carvedilol6.9%241
11
Metoprolol6.8%236
12
Levothyroxine-sodium6.3%220
13
Omeprazole6.2%217
14
Pantoprazole-sodium5.5%191
15
Lisinopril5.0%173

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports hexachlorophene side effects

47.5% of hexachlorophene adverse event reports involve female patients and 47.1% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.5%
Male47.1%
Unknown5.4%

Age group

< 20.5%
2–110.8%
12–170.5%
18–6453.3%
65+45.0%

What is hexachlorophene used for

Conditions and purposes for which patients were taking hexachlorophene when the adverse event was reported.

Acute Kidney InjuryAlopeciaAlport's SyndromeAnti-neutrophil Cytoplasmic Antibody Positive VasculitisAnxietyArthralgiaAscitesAtrial FibrillationAutomated Peritoneal DialysisAzotaemiaAlopecia ScarringBack PainBacterial PyelonephritisBipolar DisorderBlood Creatinine Increased

Showing 15 of 151 indications

Hexachlorophene brand names and reporting trend

Hexachlorophene is sold under the brand name Scrubteam Surgical Spongebrush.

Brand names

Scrubteam Surgical Spongebrush73

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking hexachlorophene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.