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Halothane Side Effects

The most commonly reported side effects of halothane include cardiac arrest, cardiac arrest, and anaphylactoid reaction, based on 197 FDA adverse event reports from 2004 to 2024.

Halothane side effects

Percentages show how often each reaction appears relative to total reports for halothane.

1
Cardiac Arrest5.6%11
2
Cardiac Arrest5.6%11
3
Anaphylactoid Reaction5.1%10
4
Pyrexia5.1%10
5
Hyperthermia Malignant4.1%8
6
Pulmonary Oedema4.1%8
7
Occupational Exposure To Product3.6%7
8
Toxicity To Various Agents3.6%7
9
Accidental Overdose3.6%7
10
Rash3.6%7
11
Ventricular Extrasystoles3.0%6
12
Tachycardia3.0%6
13
Hepatocellular Damage3.0%6
14
Drug Interaction3.0%6
15
Death3.0%6

These are voluntary reports and do not establish that halothane caused these reactions.

Report severity

92.4%Serious182 reports
20.3%Hospitalizations40 reports
24.9%Fatal49 reports

Seriousness is determined by the reporter, not by OpenClaim.

Halothane drug interactions

Other drugs that appear in adverse event reports alongside halothane. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Succinylcholine-chloride17.8%35
2
Nitrous-oxide15.7%31
3
Fentanyl14.2%28
4
Thiopental-sodium11.7%23
5
Atropine11.2%22
6
Lidocaine8.6%17
7
Propofol7.6%15
8
Diazepam7.6%15
9
Sevoflurane5.6%11
10
Isoflurane5.6%11
11
Bupivacaine5.6%11
12
Acetaminophen5.1%10
13
Atracurium-besylate5.1%10
14
Vecuronium-bromide4.6%9
15
Midazolam4.6%9

Taken alongside

1
Oxygen21.8%43
2
Nitrous-oxide18.8%37
3
Atropine16.8%33
4
Fentanyl15.7%31
5
Thiopental-sodium10.7%21
6
Atracurium-besylate7.6%15
7
Midazolam7.1%14
8
Isoflurane6.6%13
9
Vecuronium-bromide6.6%13
10
Meperidine-hydrochloride6.1%12
11
Neostigmine-methylsulfate5.6%11
12
Succinylcholine-chloride5.1%10
13
Propofol4.6%9
14
Pancuronium-bromide4.6%9
15
Lidocaine4.6%9

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports halothane side effects

39.1% of halothane adverse event reports involve female patients and 45.7% involve male patients. The largest age group is adult at 48%. These figures reflect who reports side effects, not underlying risk.

Sex

Female39.1%
Male45.7%
Unknown15.2%

Age group

< 215.3%
2–1125.2%
12–173.7%
18–6447.9%
65+8.0%

What is halothane used for

Conditions and purposes for which patients were taking halothane when the adverse event was reported.

AnaesthesiaAnal AbscessAntiviral TreatmentAsthmaAnaesthesiaCatheterisation CardiacChemical PoisoningDrug Exposure During PregnancyDrug Use For Unknown IndicationGeneral AnaesthesiaInduction And Maintenance Of AnaesthesiaInduction Of AnaesthesiaIntervertebral Disc OperationInduction And Maintenance Of AnaesthesiaInduction Of Anaesthesia

Showing 15 of 24 indications

Halothane brand names and reporting trend

Halothane is sold under the brand name Fluothane.

Brand names

Fluothane201

Quarterly reports (20042024)

2004201020202024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking halothane with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.