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Halobetasol Side Effects

The most commonly reported side effects of halobetasol include psoriasis, pruritus, and rash, based on 2,315 FDA adverse event reports from 2004 to 2025. 16.5% of reports found the drug to be ineffective.

Halobetasol side effects

Percentages show how often each reaction appears relative to total reports for halobetasol.

1
Drug Ineffective16.5%381
2
Psoriasis14.5%335
3
Pruritus7.2%166
4
Rash7.0%162
5
Product Use In Unapproved Indication5.4%124
6
Diarrhoea5.2%120
7
Pain4.9%113
8
Fatigue4.8%111
9
Nausea4.6%107
10
Headache4.5%105
11
Arthralgia4.4%101
12
Dermatitis Atopic4.3%100
13
Off Label Use4.0%92
14
Product Dose Omission Issue3.6%83
15
Skin Exfoliation3.5%80

These are voluntary reports and do not establish that halobetasol caused these reactions.

Report severity

35.2%Serious816 reports
12.5%Hospitalizations290 reports
2.2%Fatal52 reports

Seriousness is determined by the reporter, not by OpenClaim.

Halobetasol drug interactions

Other drugs that appear in adverse event reports alongside halobetasol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Dupilumab16.8%390
2
Apremilast15.8%365
3
Clobetasol-propionate7.8%181
4
Secukinumab6.9%159
5
Adalimumab5.7%133
6
Methotrexate5.5%127
7
Triamcinolone4.8%111
8
Etanercept4.6%106
9
Betamethasone3.8%89
10
Tazarotene3.5%80
11
Sodium-oxybate2.2%50
12
Risankizumab-rzaa2.2%50
13
Calcipotriene2.1%49
14
Lenalidomide2.1%48
15
Fluocinonide1.9%45

Taken alongside

1
Clobetasol-propionate15.9%367
2
Ergocalciferol15.2%352
3
Albuterol11.8%274
4
Triamcinolone11.7%271
5
Levothyroxine-sodium11.7%270
6
Acetaminophen11.4%263
7
Fluticasone11.3%261
8
Aspirin11.1%257
9
Atorvastatin-calcium10.3%239
10
Prednisone10.3%238
11
Omeprazole9.9%230
12
Calcipotriene9.2%212
13
Gabapentin8.5%197
14
Amlodipine7.9%184
15
Lisinopril7.9%183

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports halobetasol side effects

56.4% of halobetasol adverse event reports involve female patients and 38.2% involve male patients. The largest age group is adult at 69%. These figures reflect who reports side effects, not underlying risk.

Sex

Female56.4%
Male38.2%
Unknown5.4%

Age group

< 2<0.1%
2–111.2%
12–171.3%
18–6469.3%
65+28.2%

What is halobetasol used for

Conditions and purposes for which patients were taking halobetasol when the adverse event was reported.

Accidental Exposure To ProductAcneActinic KeratosisAllergy To Surgical SuturesAlopeciaArthropod BiteAdverse EventAortic AneurysmBiteBlisterCondition AggravatedCutaneous Lupus ErythematosusChronic Cutaneous Lupus ErythematosusCondition AggravatedCutaneous T-cell Lymphoma

Showing 15 of 98 indications

Halobetasol brand names and reporting trend

Halobetasol is sold under the brand name Halobetasol Propionate And Tazarotene.

Brand names

Halobetasol Propionate And Tazarotene1,697

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking halobetasol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.