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Griseofulvin Side Effects

The most commonly reported side effects of griseofulvin include headache, rash, and off label use, based on 432 FDA adverse event reports from 2004 to 2025. 7.6% of reports found the drug to be ineffective.

Griseofulvin side effects

Percentages show how often each reaction appears relative to total reports for griseofulvin.

1
Drug Ineffective7.6%33
2
Headache4.2%18
3
Rash3.0%13
4
Off Label Use3.0%13
5
Drug Hypersensitivity2.8%12
6
Drug Reaction With Eosinophilia And Systemic Symptoms2.8%12
7
Dizziness2.5%11
8
Acute Kidney Injury2.5%11
9
Headache2.5%11
10
Chronic Kidney Disease2.5%11
11
Renal Failure2.5%11
12
Fatigue2.3%10
13
Drug Interaction2.3%10
14
Delirium2.3%10
15
Pathogen Resistance2.3%10

These are voluntary reports and do not establish that griseofulvin caused these reactions.

Report severity

70.6%Serious305 reports
33.8%Hospitalizations146 reports
6.3%Fatal27 reports

Seriousness is determined by the reporter, not by OpenClaim.

Griseofulvin drug interactions

Other drugs that appear in adverse event reports alongside griseofulvin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Terbinafine9.0%39
2
Fluconazole4.4%19
3
Itraconazole4.2%18
4
Esomeprazole3.0%13
5
Amoxicillin3.0%13
6
Lenalidomide2.8%12
7
Omeprazole2.5%11
8
Etanercept2.5%11
9
Emtricitabine2.3%10
10
Tenofovir2.3%10
11
Celecoxib2.1%9
12
Ketoconazole2.1%9
13
Dupilumab2.1%9
14
Sodium-oxybate1.9%8
15
Idursulfase1.9%8

Taken alongside

1
Albuterol11.1%48
2
Acetaminophen10.9%47
3
Ibuprofen9.5%41
4
Levothyroxine-sodium7.6%33
5
Aspirin7.4%32
6
Fluticasone7.2%31
7
Ketoconazole7.2%31
8
Prednisone7.2%31
9
Furosemide6.9%30
10
Ergocalciferol6.9%30
11
Amoxicillin6.5%28
12
Amlodipine6.5%28
13
Hydrocodone6.5%28
14
Metformin6.5%28
15
Lisinopril5.8%25

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports griseofulvin side effects

44.4% of griseofulvin adverse event reports involve female patients and 46.1% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.4%
Male46.1%
Unknown9.5%

Age group

< 21.0%
2–1118.4%
12–175.6%
18–6451.6%
65+23.4%

What is griseofulvin used for

Conditions and purposes for which patients were taking griseofulvin when the adverse event was reported.

AlopeciaAnalgesic TherapyAntifungal ProphylaxisAntifungal TreatmentAspergillosisAsthmaAnti-infective TherapyAntifungal ProphylaxisAntifungal TreatmentBody TineaBody TineaCheilitisCrohn's DiseaseDermatitisDermatophytosis

Showing 15 of 57 indications

Griseofulvin brand names and reporting trend

Griseofulvin is sold under the brand name Grisactin Ultra.

Brand names

Grisactin Ultra47

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking griseofulvin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.