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Glycine Side Effects

The most commonly reported side effects of glycine include fatigue, nausea, and dizziness, based on 1,532 FDA adverse event reports from 2004 to 2025. 5.5% of reports found the drug to be ineffective.

Glycine side effects

Percentages show how often each reaction appears relative to total reports for glycine.

1
Drug Ineffective5.5%84
2
Fatigue5.2%80
3
Nausea4.9%75
4
Dizziness4.9%75
5
Anaemia4.2%65
6
Headache4.2%65
7
Off Label Use4.2%64
8
Pneumonia3.9%60
9
Diarrhoea3.8%58
10
Bradycardia3.8%58
11
Atrial Fibrillation3.7%56
12
Covid-193.7%56
13
Insomnia3.4%52
14
Dyspnoea3.3%50
15
General Physical Health Deterioration3.3%50

These are voluntary reports and do not establish that glycine caused these reactions.

Report severity

87.3%Serious1,338 reports
53.8%Hospitalizations824 reports
13.4%Fatal206 reports

Seriousness is determined by the reporter, not by OpenClaim.

Glycine drug interactions

Other drugs that appear in adverse event reports alongside glycine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Furosemide4.3%66
2
Pantoprazole-sodium4.1%63
3
Amoxicillin3.5%54
4
Tacrolimus3.5%53
5
Acetaminophen3.4%52
6
Cholecalciferol3.3%51
7
Sodium-bicarbonate3.2%49
8
Levetiracetam3.2%49
9
Torsemide3.2%49
10
Sodium-oxybate2.9%44
11
Darbepoetin-alfa2.7%42
12
Carvedilol2.6%40
13
Mycophenolate2.5%39
14
Tamsulosin-hydrochloride2.5%38
15
Candesartan-cilexetil2.3%36

Taken alongside

1
Acetaminophen12.6%193
2
Pantoprazole-sodium12.1%186
3
Ergocalciferol12.1%185
4
Aspirin11.0%169
5
Levothyroxine-sodium10.7%164
6
Omeprazole10.3%158
7
Amlodipine9.7%149
8
Furosemide9.6%147
9
Folic-acid8.2%125
10
Cyanocobalamin7.5%115
11
Atorvastatin-calcium7.4%114
12
Cholecalciferol6.8%104
13
Ascorbic-acid6.4%98
14
Prednisolone6.3%96
15
Metoprolol6.3%96

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports glycine side effects

49.5% of glycine adverse event reports involve female patients and 43.4% involve male patients. The largest age group is adult at 48%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.5%
Male43.4%
Unknown7.1%

Age group

< 21.9%
2–113.8%
12–172.0%
18–6447.8%
65+44.5%

What is glycine used for

Conditions and purposes for which patients were taking glycine when the adverse event was reported.

Abortion SpontaneousAcute Graft Versus Host DiseaseAdverse EventAmyotrophic Lateral SclerosisAnaemiaAntiviral ProphylaxisAspartate Aminotransferase IncreasedAstheniaAtrial FibrillationAbdominal DistensionAgitationAlanine Aminotransferase IncreasedAnaemiaAnaemia ProphylaxisAnti-neutrophil Cytoplasmic Antibody Positive Vasculitis

Showing 15 of 172 indications

Glycine brand names and reporting trend

Glycine is sold under the brand name Glycine 1.5% In Plastic Container.

Brand names

Glycine 1.5% In Plastic Container1,545

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking glycine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.