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Glucagon Side Effects

The most commonly reported side effects of glucagon include dyspnoea, acute kidney injury, and hypotension, based on 5,015 FDA adverse event reports from 2004 to 2025. 8.0% of reports found the drug to be ineffective.

Glucagon side effects

Percentages show how often each reaction appears relative to total reports for glucagon.

1
Drug Ineffective8.0%400
2
Dyspnoea7.7%388
3
Acute Kidney Injury7.1%357
4
Hypotension6.1%305
5
Hypoglycaemia5.8%289
6
Nausea5.6%283
7
Condition Aggravated5.3%266
8
Death5.0%250
9
Vomiting4.7%238
10
Haemoptysis4.6%233
11
Toxicity To Various Agents4.6%230
12
Anxiety4.5%228
13
Off Label Use4.5%225
14
Pain In Extremity4.4%219
15
Headache4.1%208

These are voluntary reports and do not establish that glucagon caused these reactions.

Report severity

77.3%Serious3,875 reports
47.4%Hospitalizations2,379 reports
15.3%Fatal766 reports

Seriousness is determined by the reporter, not by OpenClaim.

Glucagon drug interactions

Other drugs that appear in adverse event reports alongside glucagon. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Insulin12.7%639
2
Pantoprazole-sodium5.1%256
3
Amlodipine4.6%231
4
Metformin4.6%230
5
Cefuroxime4.2%209
6
Epinephrine4.1%208
7
Prednisone3.9%198
8
Furosemide3.8%191
9
Candesartan-cilexetil3.7%186
10
Hydrochlorothiazide3.7%185
11
Omeprazole3.7%184
12
Calcium-carbonate3.6%181
13
Levofloxacin3.6%180
14
Azathioprine3.6%180
15
Albuterol3.6%179

Taken alongside

1
Insulin46.6%2,335
2
Acetaminophen26.5%1,329
3
Albuterol19.7%989
4
Ondansetron18.1%907
5
Aspirin18.0%901
6
Ergocalciferol15.9%798
7
Atorvastatin-calcium15.4%773
8
Dextrose15.2%760
9
Furosemide15.0%753
10
Pantoprazole-sodium13.0%654
11
Gabapentin12.3%617
12
Levothyroxine-sodium12.1%608
13
Sodium-chloride11.9%597
14
Fluticasone11.7%587
15
Metformin11.2%560

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports glucagon side effects

47.5% of glucagon adverse event reports involve female patients and 43.5% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.5%
Male43.5%
Unknown9.0%

Age group

< 21.8%
2–112.0%
12–174.0%
18–6453.9%
65+38.4%

What is glucagon used for

Conditions and purposes for which patients were taking glucagon when the adverse event was reported.

Abdominal ExplorationActh Stimulation TestAdverse EventAccidental OverdoseAnaesthesiaAnaphylactic ReactionAnaphylactic ShockBiliary Tract Dilation ProcedureBlood GlucagonBlood GlucoseBlood Glucose AbnormalBlood Glucose DecreasedBlood Glucose IncreasedBowel PreparationBradycardia

Showing 15 of 197 indications

Glucagon brand names and reporting trend

Glucagon is sold under the brand name Gvoke Vialdx.

Brand names

Gvoke Vialdx4,660

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking glucagon with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.